Cargando…

Sulindac, a non-steroidal anti-inflammatory drug, mediates breast cancer inhibition as an immune modulator

The cooperation of adaptive immunity with pharmacologic therapy influences cancer progression. Though non-steroidal anti-inflammatory drugs (NSAIDs) have a long history of cancer prevention, it is unclear whether adaptive immune system affects the action of those drugs. In present study, we revealed...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yin, Tao, Wang, Guoping, Ye, Tinghong, Wang, Yongsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725989/ https://www.ncbi.nlm.nih.gov/pubmed/26777116 http://dx.doi.org/10.1038/srep19534

Ejemplares similares

The effect of sulindac, a non-steroidal anti-inflammatory drug, attenuates inflammation and fibrosis in a mouse model of chronic pancreatitis
por: Bai, Han, et al.
Publicado: (2012)

New use for an old drug: COX‐independent anti‐inflammatory effects of sulindac in models of cystic fibrosis
por: Rocca, Jérémy, et al.
Publicado: (2016)

Sulindac sulfide as a non-immune suppressive γ-secretase modulator to target triple-negative breast cancer
por: Hossain, Fokhrul, et al.
Publicado: (2023)

Novel sulindac derivatives: synthesis, characterisation, evaluation of antioxidant, analgesic, anti-inflammatory, ulcerogenic and COX-2 inhibition activity
por: Bhat, Mashooq A., et al.
Publicado: (2020)

Dopamine receptor antagonist thioridazine inhibits tumor growth in a murine breast cancer model
por: YIN, TAO, et al.
Publicado: (2015)

Chemoprevention of Colon Cancer by DFMO, Sulindac, and NO-Sulindac Administered Individually or in Combinations in F344 Rats
por: Madka, Venkateshwar, et al.
Publicado: (2023)

Phospho-sulindac inhibits pancreatic cancer growth: NFATc1 as a drug resistance candidate
por: MURRAY, ONIKA T., et al.
Publicado: (2013)

Analysis of the Dissolution Mechanism of Drugs into Polymers: The Case of the PVP/Sulindac System
por: Latreche, Mansour, et al.
Publicado: (2023)

Sulindac metabolites inhibit epidermal growth factor receptor activation and expression
por: Pangburn, Heather A, et al.
Publicado: (2005)

Sulindac acetohydrazide derivative attenuates against cisplatin induced organ damage by modulation of antioxidant and inflammatory signaling pathways
por: Razak, Suhail, et al.
Publicado: (2022)

Sulindac for stroke treatment: neuroprotective mechanism and therapy
por: Modi, Jigar Pravinchandra, et al.
Publicado: (2014)

Amine Containing Analogs of Sulindac for Cancer Prevention
por: Mathew, Bini, et al.
Publicado: (2018)

Oxazole and thiazole analogs of sulindac for cancer prevention
por: Mathew, Bini, et al.
Publicado: (2018)

Combination oral antiangiogenic therapy with thalidomide and sulindac inhibits tumour growth in rabbits
por: Verheul, H M W, et al.
Publicado: (1999)

Selenium and sulindac are synergistic to inhibit intestinal tumorigenesis in Apc/p21 mice
por: Bi, Xiuli, et al.
Publicado: (2013)

Inhibitory Effect of Herbal Remedy PERVIVO and Anti-Inflammatory Drug Sulindac on L-1 Sarcoma Tumor Growth and Tumor Angiogenesis in Balb/c Mice
por: Skopiński, P., et al.
Publicado: (2013)

The Role of Non-Steroidal Anti-Inflammatory Drugs in the Chemoprevention of Breast Cancer
por: Horn, Sarah L., et al.
Publicado: (2010)

Non-Steroidal Anti-Inflammatory Drugs Loaded to Micelles for the Modulation of Their Water Solubility
por: Banti, Christina N., et al.
Publicado: (2023)

Sulindac plus a phospholipid is effective for polyp reduction and safer than sulindac alone in a mouse model of colorectal cancer development
por: Davis, Jennifer S., et al.
Publicado: (2020)

Sulindac Derivatives That Activate the Peroxisome Proliferator-activated Receptor γ but Lack Cyclooxygenase Inhibition
por: Felts, Andrew S., et al.
Publicado: (2008)

Non Steroidal Anti-Inflammatory Drugs and Inflammatory Bowel Disease
por: Klein, Amir, et al.
Publicado: (2010)

NMR-Guided Repositioning of Non-Steroidal Anti-Inflammatory Drugs into Tight Junction Modulators
por: Tenno, Takeshi, et al.
Publicado: (2021)

Novel Non-Cyclooxygenase Inhibitory Derivative of Sulindac Inhibits Breast Cancer Cell Growth In Vitro and Reduces Mammary Tumorigenesis in Rats
por: Tinsley, Heather N., et al.
Publicado: (2023)

Sulindac sulfide inhibits colon cancer cell growth and downregulates specificity protein transcription factors
por: Li, Xi, et al.
Publicado: (2015)

Sulindac Enhances the Killing of Cancer Cells Exposed to Oxidative Stress
por: Marchetti, Maria, et al.
Publicado: (2009)

Sulindac Prevents Esophageal Adenocarcinomas Induced by Gastroduodenal Reflux in Rats
por: Kim, Sung Wook, et al.
Publicado: (2007)

A Desmoid Tumor Responding to Systemic Therapy With Tamoxifen and Sulindac
por: Choudhury, Hasan, et al.
Publicado: (2023)

Non-Steroidal Anti-Inflammatory Drug-Induced Enteropathy
por: Lim, Yun Jeong, et al.
Publicado: (2012)

Non-steroid anti-inflammatory drugs, prostaglandins, and cancer
por: Allaj, Viola, et al.
Publicado: (2013)

Role of Non-Steroidal Anti-Inflammatory Drugs in Gynecology
por: Livshits, Anna, et al.
Publicado: (2010)

Non-steroidal anti-inflammatory drug-induced enteropathy
por: Shin, Sung Jae, et al.
Publicado: (2017)

Non-Steroidal Anti-Inflammatory Drugs and Peptic Ulceration
por: Clinch, D., et al.
Publicado: (1987)

Pharmacogenomics of Hypersensitivity to Non-steroidal Anti-inflammatory Drugs
por: Trinh, Hoang Kim Tu, et al.
Publicado: (2021)

Non‐steroidal anti‐inflammatory drugs in equine orthopaedics
por: Jacobs, Carrie C., et al.
Publicado: (2022)

Sulindac inhibits tumor cell invasion by suppressing NF-κB mediated transcription of microRNAs
por: Li, Xiaobo, et al.
Publicado: (2012)

Identification of the Effects of Aspirin and Sulindac Sulfide on the Inhibition of HMGA2-Mediated Oncogenic Capacities in Colorectal Cancer
por: Ekanem, Titus Ime, et al.
Publicado: (2020)

Cyclin G2, a novel target of sulindac to inhibit cell cycle progression in colorectal cancer
por: Zhao, Hongyou, et al.
Publicado: (2020)

The anti-breast cancer stem cell properties of gold(i)-non-steroidal anti-inflammatory drug complexes
por: Johnson, Alice, et al.
Publicado: (2022)

The Anti-Breast Cancer Stem Cell Potency of Copper(I)-Non-Steroidal Anti-Inflammatory Drug Complexes
por: Johnson, Alice, et al.
Publicado: (2023)

Effects of FMO3 Polymorphisms on Pharmacokinetics of Sulindac in Chinese Healthy Male Volunteers
por: Tang, Yong-Jun, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_92tqhhg8b9vb6s5cbna5v0mmeu