Cargando…

Immunization against an IL-6 peptide induces anti-IL-6 antibodies and modulates the Delayed-Type Hypersensitivity reaction in cynomolgus monkeys

Interleukin-6 (IL-6) overproduction has been involved in the pathogenesis of several chronic inflammatory diseases and the administration of an anti-IL-6 receptor monoclonal antibody has been proven clinically efficient to treat them. However, the drawbacks of monoclonal antibodies have led our grou...

Descripción completa

Detalles Bibliográficos
Autores principales:	Desallais, Lucille, Bouchez, Caroline, Mouhsine, Hadley, Moreau, Gabriel, Ratsimandresy, Rojo, Montes, Matthieu, Do, Hervé, Quintin-Colonna, Françoise, Zagury, Jean-François
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726013/ https://www.ncbi.nlm.nih.gov/pubmed/26782790 http://dx.doi.org/10.1038/srep19549

Ejemplares similares

Targeting IL-6 by both passive or active immunization strategies prevents bleomycin-induced skin fibrosis
por: Desallais, Lucille, et al.
Publicado: (2014)

Identification of an in vivo orally active dual-binding protein-protein interaction inhibitor targeting TNFα through combined in silico/in vitro/in vivo screening
por: Mouhsine, Hadley, et al.
Publicado: (2017)

Development of a Delayed-Type Hypersensitivity (DTH) Model in the Cynomolgus Monkey
por: Bouchez, Caroline, et al.
Publicado: (2012)

The AIM2 inflammasome is a central regulator of intestinal homeostasis through the IL-18/IL-22/STAT3 pathway
por: Ratsimandresy, Rojo A, et al.
Publicado: (2017)

Modeling the pharmacokinetic‐pharmacodynamic relationship of the monoclonal anti‐macaque‐IL‐15 antibody Hu714MuXHu in cynomolgus monkeys
por: Pan, Wei. J., et al.
Publicado: (2016)

Keratoconus in a Cynomolgus Monkey
por: Kodama, Rinya, et al.
Publicado: (2010)

Erythrocytes of the Rhesus and Cynomolgus Monkeys
por: Stingo, Vincenzo
Publicado: (2019)

The Long Terminal Repeats of ERV6 Are Activated in Pre-Implantation Embryos of Cynomolgus Monkey
por: Duan, Kui, et al.
Publicado: (2021)

Circulating monocytes accelerate acute liver failure by IL‐6 secretion in monkey
por: Guo, Gang, et al.
Publicado: (2018)

Bilateral Cataract in a Cynomolgus Monkey
por: Sasaki, Yuji, et al.
Publicado: (2011)

Chemically Modified Interleukin-6 Aptamer Inhibits Development of Collagen-Induced Arthritis in Cynomolgus Monkeys
por: Hirota, Masao, et al.
Publicado: (2016)

Codelivery of IL-7 Augments Multigenic HCV DNA Vaccine-induced Antibody as well as Broad T Cell Responses in Cynomolgus Monkeys
por: Park, Su-Hyung, et al.
Publicado: (2010)

Association of Polymorphisms of IL-6 Pathway Genes (IL6, IL6R and IL6ST) with COVID-19 Severity in an Amazonian Population
por: Rodrigues, Fabíola Brasil Barbosa, et al.
Publicado: (2023)

Origins of Cortical GABAergic Neurons in the Cynomolgus Monkey
por: Petanjek, Zdravko, et al.
Publicado: (2009)

Porencephaly in a Cynomolgus Monkey (Macaca Fascicularis)
por: Hirowatari, Chika, et al.
Publicado: (2012)

Bartonella quintana in Cynomolgus Monkey (Macaca fascicularis)
por: O'Rourke, Laurie G., et al.
Publicado: (2005)

Epigenetic Changes with Dietary Soy in Cynomolgus Monkeys
por: Howard, Timothy D., et al.
Publicado: (2011)

Characteristics of histologically confirmed endometriosis in cynomolgus monkeys
por: Nishimoto-Kakiuchi, A., et al.
Publicado: (2016)

Granulovacuolar Degeneration in Brains of Senile Cynomolgus Monkeys
por: Darusman, Huda S., et al.
Publicado: (2019)

Multiplex precise base editing in cynomolgus monkeys
por: Zhang, Wenhui, et al.
Publicado: (2020)

The cerebral artery in cynomolgus monkeys (Macaca fascicularis)
por: Tsuji, Keiichi, et al.
Publicado: (2022)

Cynomolgus macaque IL37 polymorphism and control of SIV infection
por: Shiina, Takashi, et al.
Publicado: (2019)

IL-6 Trans-Signaling via the Soluble IL-6 Receptor: Importance for the Pro-Inflammatory Activities of IL-6
por: Rose-John, Stefan
Publicado: (2012)

IL-6 is Upregulated in Late-Stage Disease in Monkeys Experimentally Infected with Trypanosoma brucei rhodesiense
por: Nyawira Maranga, Dawn, et al.
Publicado: (2013)

IL6/IL6R genetic diversity and plasma IL6 levels in bipolar disorder: An Indo-French study
por: Sundaresh, Aparna, et al.
Publicado: (2019)

IL-6 Quotient (The Ratio of Cerebrospinal Fluid IL-6 to Serum IL-6) as a Biomarker of an Unruptured Intracranial Aneurysm
por: Kamińska, Joanna, et al.
Publicado: (2021)

Dissecting the IL‐6 pathway in cardiometabolic disease: A Mendelian randomization study on both IL6 and IL6R
por: Cupido, Arjen J., et al.
Publicado: (2022)

The function of the soluble interleukin 6 (IL-6) receptor in vivo: sensitization of human soluble IL-6 receptor transgenic mice towards IL- 6 and prolongation of the plasma half-life of IL-6
Publicado: (1996)

Comparative maturation of cynomolgus monkey oocytes in vivo and in vitro
por: Yin, Hang, et al.
Publicado: (2006)

Plasmodium vivax Seroprevalence in Bred Cynomolgus Monkeys, China
por: Elmore, David B.
Publicado: (2011)

Plasmodium vivax Seroprevalence in Bred Cynomolgus Monkeys, China
por: Li, Hai-Long, et al.
Publicado: (2011)

Transcriptome reconstruction and annotation of cynomolgus and African green monkey
por: Lee, Albert, et al.
Publicado: (2014)

Granulomatous Nephritis Consistent with Malakoplakia in a Cynomolgus Monkey
por: Taketa, Yoshikazu, et al.
Publicado: (2013)

Malaria in cynomolgus monkeys used in toxicity studies in Japan
por: Ohta, Etsuko, et al.
Publicado: (2015)

Circulating liver-specific microRNAs in cynomolgus monkeys
por: Iguchi, Takuma, et al.
Publicado: (2017)

Reemergence of Reston ebolavirus in Cynomolgus Monkeys, the Philippines, 2015
por: Demetria, Catalino, et al.
Publicado: (2018)

Diarrhea in newborn cynomolgus monkeys infected with human rotavirus
por: Majer, M., et al.
Publicado: (1978)

A cynomolgus monkey with naturally occurring Parkinson's disease
por: Li, Hao, et al.
Publicado: (2020)

Effect of Dietetic Obesity on Testicular Transcriptome in Cynomolgus Monkeys
por: Zhang, Yanru, et al.
Publicado: (2023)

Quantification of Non-Motor Symptoms in Parkinsonian Cynomolgus Monkeys
por: Bao, Yu, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ksifpm2fm3i5bubjtmj7vvrb4l