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Cytotoxic polyfunctionality maturation of cytomegalovirus-pp65-specific CD4 + and CD8 + T-cell responses in older adults positively correlates with response size
Cytomegalovirus (CMV) infection is one of the most common persistent viral infections in humans worldwide and is epidemiologically associated with many adverse health consequences during aging. Previous studies yielded conflicting results regarding whether large, CMV-specific T-cell expansions maint...
Autores principales: | Chiu, Yen-Ling, Lin, Chung-Hao, Sung, Bo-Yi, Chuang, Yi-Fang, Schneck, Jonathan P., Kern, Florian, Pawelec, Graham, Wang, George C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726016/ https://www.ncbi.nlm.nih.gov/pubmed/26778409 http://dx.doi.org/10.1038/srep19227 |
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