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Molecular Combing of Single DNA Molecules on the 10 Megabase Scale

DNA combing allows the investigation of DNA replication on genomic single DNA molecules, but the lengths that can be analysed have been restricted to molecules of 200–500 kb. We have improved the DNA combing procedure so that DNA molecules can be analysed up to the length of entire chromosomes in fi...

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Detalles Bibliográficos
Autores principales: Kaykov, Atanas, Taillefumier, Thibaud, Bensimon, Aaron, Nurse, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726065/
https://www.ncbi.nlm.nih.gov/pubmed/26781994
http://dx.doi.org/10.1038/srep19636

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