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Transcription factor NFAT1 controls allergic contact hypersensitivity through regulation of activation induced cell death program
Allergic contact hypersensitivity (CHS) is an inflammatory skin disease mediated by allergen specific T cells. In this study, we investigated the role of transcription factor NFAT1 in the pathogenesis of contact hypersensitivity. NFAT1 knock out (KO) mice spontaneously developed CHS-like skin inflam...
Autores principales: | Kwon, Ho-Keun, Kim, Gi-Cheon, Hwang, Ji Sun, Kim, Young, Chae, Chang-Suk, Nam, Jong Hee, Jun, Chang-Duk, Rudra, Dipayan, Surh, Charles D., Im, Sin-Hyeog |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726067/ https://www.ncbi.nlm.nih.gov/pubmed/26777750 http://dx.doi.org/10.1038/srep19453 |
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