Dietary component isorhamnetin is a PPARγ antagonist and ameliorates metabolic disorders induced by diet or leptin deficiency

Studies on peroxisome proliferator-activated receptor (PPAR)-γ ligands have been focused on agonists. However, PPARγ activation may induce obesity and nonalcoholic fatty liver disease (NAFLD), one of the most challenging medical conditions. Here, we identified that isorhamnetin, a naturally occurrin...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Gu, Ming, Cai, Wujie, Yu, Lijing, Feng, Li, Zhang, Lu, Zang, Qingqing, Wang, Yahui, Wang, Dongshan, Chen, Hui, Tong, Qingchun, Ji, Guang, Huang, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726074/
https://www.ncbi.nlm.nih.gov/pubmed/26775807
http://dx.doi.org/10.1038/srep19288

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