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A sex-inducing pheromone triggers cell cycle arrest and mate attraction in the diatom Seminavis robusta

Although sexual reproduction is believed to play a major role in the high diversification rates and species richness of diatoms, a mechanistic understanding of diatom life cycle control is virtually lacking. Diatom sexual signalling is controlled by a complex, yet largely unknown, pheromone system....

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Autores principales: Moeys, Sara, Frenkel, Johannes, Lembke, Christine, Gillard, Jeroen T. F., Devos, Valerie, Van den Berge, Koen, Bouillon, Barbara, Huysman, Marie J. J., De Decker, Sam, Scharf, Julia, Bones, Atle, Brembu, Tore, Winge, Per, Sabbe, Koen, Vuylsteke, Marnik, Clement, Lieven, De Veylder, Lieven, Pohnert, Georg, Vyverman, Wim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726125/
https://www.ncbi.nlm.nih.gov/pubmed/26786712
http://dx.doi.org/10.1038/srep19252
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author Moeys, Sara
Frenkel, Johannes
Lembke, Christine
Gillard, Jeroen T. F.
Devos, Valerie
Van den Berge, Koen
Bouillon, Barbara
Huysman, Marie J. J.
De Decker, Sam
Scharf, Julia
Bones, Atle
Brembu, Tore
Winge, Per
Sabbe, Koen
Vuylsteke, Marnik
Clement, Lieven
De Veylder, Lieven
Pohnert, Georg
Vyverman, Wim
author_facet Moeys, Sara
Frenkel, Johannes
Lembke, Christine
Gillard, Jeroen T. F.
Devos, Valerie
Van den Berge, Koen
Bouillon, Barbara
Huysman, Marie J. J.
De Decker, Sam
Scharf, Julia
Bones, Atle
Brembu, Tore
Winge, Per
Sabbe, Koen
Vuylsteke, Marnik
Clement, Lieven
De Veylder, Lieven
Pohnert, Georg
Vyverman, Wim
author_sort Moeys, Sara
collection PubMed
description Although sexual reproduction is believed to play a major role in the high diversification rates and species richness of diatoms, a mechanistic understanding of diatom life cycle control is virtually lacking. Diatom sexual signalling is controlled by a complex, yet largely unknown, pheromone system. Here, a sex-inducing pheromone (SIP(+)) of the benthic pennate diatom Seminavis robusta was identified by comparative metabolomics, subsequently purified, and physicochemically characterized. Transcriptome analysis revealed that SIP(+) triggers the switch from mitosis-to-meiosis in the opposing mating type, coupled with the transcriptional induction of proline biosynthesis genes, and the release of the proline-derived attraction pheromone. The induction of cell cycle arrest by a pheromone, chemically distinct from the one used to attract the opposite mating type, highlights the existence of a sophisticated mechanism to increase chances of mate finding, while keeping the metabolic losses associated with the release of an attraction pheromone to a minimum.
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spelling pubmed-47261252016-01-27 A sex-inducing pheromone triggers cell cycle arrest and mate attraction in the diatom Seminavis robusta Moeys, Sara Frenkel, Johannes Lembke, Christine Gillard, Jeroen T. F. Devos, Valerie Van den Berge, Koen Bouillon, Barbara Huysman, Marie J. J. De Decker, Sam Scharf, Julia Bones, Atle Brembu, Tore Winge, Per Sabbe, Koen Vuylsteke, Marnik Clement, Lieven De Veylder, Lieven Pohnert, Georg Vyverman, Wim Sci Rep Article Although sexual reproduction is believed to play a major role in the high diversification rates and species richness of diatoms, a mechanistic understanding of diatom life cycle control is virtually lacking. Diatom sexual signalling is controlled by a complex, yet largely unknown, pheromone system. Here, a sex-inducing pheromone (SIP(+)) of the benthic pennate diatom Seminavis robusta was identified by comparative metabolomics, subsequently purified, and physicochemically characterized. Transcriptome analysis revealed that SIP(+) triggers the switch from mitosis-to-meiosis in the opposing mating type, coupled with the transcriptional induction of proline biosynthesis genes, and the release of the proline-derived attraction pheromone. The induction of cell cycle arrest by a pheromone, chemically distinct from the one used to attract the opposite mating type, highlights the existence of a sophisticated mechanism to increase chances of mate finding, while keeping the metabolic losses associated with the release of an attraction pheromone to a minimum. Nature Publishing Group 2016-01-20 /pmc/articles/PMC4726125/ /pubmed/26786712 http://dx.doi.org/10.1038/srep19252 Text en Copyright © 2016, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Moeys, Sara
Frenkel, Johannes
Lembke, Christine
Gillard, Jeroen T. F.
Devos, Valerie
Van den Berge, Koen
Bouillon, Barbara
Huysman, Marie J. J.
De Decker, Sam
Scharf, Julia
Bones, Atle
Brembu, Tore
Winge, Per
Sabbe, Koen
Vuylsteke, Marnik
Clement, Lieven
De Veylder, Lieven
Pohnert, Georg
Vyverman, Wim
A sex-inducing pheromone triggers cell cycle arrest and mate attraction in the diatom Seminavis robusta
title A sex-inducing pheromone triggers cell cycle arrest and mate attraction in the diatom Seminavis robusta
title_full A sex-inducing pheromone triggers cell cycle arrest and mate attraction in the diatom Seminavis robusta
title_fullStr A sex-inducing pheromone triggers cell cycle arrest and mate attraction in the diatom Seminavis robusta
title_full_unstemmed A sex-inducing pheromone triggers cell cycle arrest and mate attraction in the diatom Seminavis robusta
title_short A sex-inducing pheromone triggers cell cycle arrest and mate attraction in the diatom Seminavis robusta
title_sort sex-inducing pheromone triggers cell cycle arrest and mate attraction in the diatom seminavis robusta
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726125/
https://www.ncbi.nlm.nih.gov/pubmed/26786712
http://dx.doi.org/10.1038/srep19252
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