Cargando…

Positive changes in ideal CVH metrics reduce the incidence of stroke

The American Heart Association defined 7 ideal cardiovascular health (CVH) metrics and the benefits of them in reducing the incidence of stroke are well established, but it is unclear whether changes in them alter stroke risk. We calculated the changes of 7 ideal CVH metrics from 2006 to 2008 among...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Xiaomeng, Wang, Anxin, Liu, Xiaoxue, An, Shasha, Chen, Shuohua, Wang, Yilong, Wang, Yongjun, Wu, Shouling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726201/
https://www.ncbi.nlm.nih.gov/pubmed/26790535
http://dx.doi.org/10.1038/srep19673
_version_ 1782411770213695488
author Yang, Xiaomeng
Wang, Anxin
Liu, Xiaoxue
An, Shasha
Chen, Shuohua
Wang, Yilong
Wang, Yongjun
Wu, Shouling
author_facet Yang, Xiaomeng
Wang, Anxin
Liu, Xiaoxue
An, Shasha
Chen, Shuohua
Wang, Yilong
Wang, Yongjun
Wu, Shouling
author_sort Yang, Xiaomeng
collection PubMed
description The American Heart Association defined 7 ideal cardiovascular health (CVH) metrics and the benefits of them in reducing the incidence of stroke are well established, but it is unclear whether changes in them alter stroke risk. We calculated the changes of 7 ideal CVH metrics from 2006 to 2008 among 64,373 participants in the Kailuan study. We tested whether changes in the numbers and total scores for the CVH metrics were associated with the incidence of stroke in the 4.89 person-years follow-up. Cox regression modeling was used to estimate the risk of stroke. By year 2008, CVH metrics number of 32.54% participants improved (change ≥+1); 31.90% deteriorated (≤−1); 35.56% stayed the same; In the follow-up,we identified1,182 incident stroke events. Each increase in CVH metrics and every 1-point increase in total CVH score from 2006 to 2008 were associated with reduced odds of total stroke (hazard ratio = 0.87; 95% confidence interval; 0.83–0.92 and 0.89[0.86–0.92] respectively), after adjusting for age, gender, educational level, income and scores for the metrics of ideal CVH at baseline. Positive changes in ideal CVH metrics reduce the incidence of stroke. Our results support the concept that achieving ideal CVH helps to prevent stroke.
format Online
Article
Text
id pubmed-4726201
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-47262012016-01-27 Positive changes in ideal CVH metrics reduce the incidence of stroke Yang, Xiaomeng Wang, Anxin Liu, Xiaoxue An, Shasha Chen, Shuohua Wang, Yilong Wang, Yongjun Wu, Shouling Sci Rep Article The American Heart Association defined 7 ideal cardiovascular health (CVH) metrics and the benefits of them in reducing the incidence of stroke are well established, but it is unclear whether changes in them alter stroke risk. We calculated the changes of 7 ideal CVH metrics from 2006 to 2008 among 64,373 participants in the Kailuan study. We tested whether changes in the numbers and total scores for the CVH metrics were associated with the incidence of stroke in the 4.89 person-years follow-up. Cox regression modeling was used to estimate the risk of stroke. By year 2008, CVH metrics number of 32.54% participants improved (change ≥+1); 31.90% deteriorated (≤−1); 35.56% stayed the same; In the follow-up,we identified1,182 incident stroke events. Each increase in CVH metrics and every 1-point increase in total CVH score from 2006 to 2008 were associated with reduced odds of total stroke (hazard ratio = 0.87; 95% confidence interval; 0.83–0.92 and 0.89[0.86–0.92] respectively), after adjusting for age, gender, educational level, income and scores for the metrics of ideal CVH at baseline. Positive changes in ideal CVH metrics reduce the incidence of stroke. Our results support the concept that achieving ideal CVH helps to prevent stroke. Nature Publishing Group 2016-01-21 /pmc/articles/PMC4726201/ /pubmed/26790535 http://dx.doi.org/10.1038/srep19673 Text en Copyright © 2016, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Yang, Xiaomeng
Wang, Anxin
Liu, Xiaoxue
An, Shasha
Chen, Shuohua
Wang, Yilong
Wang, Yongjun
Wu, Shouling
Positive changes in ideal CVH metrics reduce the incidence of stroke
title Positive changes in ideal CVH metrics reduce the incidence of stroke
title_full Positive changes in ideal CVH metrics reduce the incidence of stroke
title_fullStr Positive changes in ideal CVH metrics reduce the incidence of stroke
title_full_unstemmed Positive changes in ideal CVH metrics reduce the incidence of stroke
title_short Positive changes in ideal CVH metrics reduce the incidence of stroke
title_sort positive changes in ideal cvh metrics reduce the incidence of stroke
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726201/
https://www.ncbi.nlm.nih.gov/pubmed/26790535
http://dx.doi.org/10.1038/srep19673
work_keys_str_mv AT yangxiaomeng positivechangesinidealcvhmetricsreducetheincidenceofstroke
AT wanganxin positivechangesinidealcvhmetricsreducetheincidenceofstroke
AT liuxiaoxue positivechangesinidealcvhmetricsreducetheincidenceofstroke
AT anshasha positivechangesinidealcvhmetricsreducetheincidenceofstroke
AT chenshuohua positivechangesinidealcvhmetricsreducetheincidenceofstroke
AT wangyilong positivechangesinidealcvhmetricsreducetheincidenceofstroke
AT wangyongjun positivechangesinidealcvhmetricsreducetheincidenceofstroke
AT wushouling positivechangesinidealcvhmetricsreducetheincidenceofstroke