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Noninvasive, Targeted, and Non-Viral Ultrasound-Mediated GDNF-Plasmid Delivery for Treatment of Parkinson’s Disease

Glial cell line-derived neurotrophic factor (GDNF) supports the growth and survival of dopaminergic neurons. CNS gene delivery currently relies on invasive intracerebral injection to transit the blood-brain barrier. Non-viral gene delivery via systematic transvascular route is an attractive alternat...

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Detalles Bibliográficos
Autores principales:	Fan, Ching-Hsiang, Ting, Chien-Yu, Lin, Chung‐Yin, Chan, Hong-Lin, Chang, Yuan-Chih, Chen, You-Yin, Liu, Hao-Li, Yeh, Chih-Kuang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726227/ https://www.ncbi.nlm.nih.gov/pubmed/26786201 http://dx.doi.org/10.1038/srep19579

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