IL-10-produced by human transitional B-cells down-regulates CD86 expression on B-cells leading to inhibition of CD4(+)T-cell responses

A novel subset of human regulatory B-cells has recently been described. They arise from within the transitional B-cell subpopulation and are characterised by the production of IL-10. They appear to be of significant importance in regulating T-cell immunity in vivo. Despite this important function, t...

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Detalles Bibliográficos
Autores principales: Nova-Lamperti, Estefania, Fanelli, Giorgia, Becker, Pablo D., Chana, Prabhjoat, Elgueta, Raul, Dodd, Philippa C., Lord, Graham M., Lombardi, Giovanna, Hernandez-Fuentes, Maria P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726240/
https://www.ncbi.nlm.nih.gov/pubmed/26795594
http://dx.doi.org/10.1038/srep20044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726240/
https://www.ncbi.nlm.nih.gov/pubmed/26795594
http://dx.doi.org/10.1038/srep20044

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