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AMPK Suppresses Connexin43 Expression in the Bladder and Ameliorates Voiding Dysfunction in Cyclophosphamide-induced Mouse Cystitis
Bladder voiding dysfunction is closely related to local oxidation, inflammation, and enhanced channel activities. Given that the AMP-activated protein kinase (AMPK) has anti-oxidative, anti-inflammatory and channel-inhibiting properties, we examined whether and how AMPK affected bladder activity. AM...
Autores principales: | Zhang, Xiling, Yao, Jian, Gao, Kun, Chi, Yuan, Mitsui, Takahiko, Ihara, Tatsuya, Sawada, Norifumi, Kamiyama, Manabu, Fan, Jianglin, Takeda, Masayuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726257/ https://www.ncbi.nlm.nih.gov/pubmed/26806558 http://dx.doi.org/10.1038/srep19708 |
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