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Heterologously-expressed and Liposome-reconstituted Human Transient Receptor Potential Melastatin 4 Channel (TRPM4) is a Functional Tetramer

Mutation, irregular expression and sustained activation of the Transient Receptor Potential Channel, type Melastatin 4 (TRPM4), have been linked to various cardiovascular diseases. However, much remains unknown about the structure of this important ion channel. Here, we have purified a heterologousl...

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Detalles Bibliográficos
Autores principales:	Constantine, Maryrose, Liew, Chu Kong, Lo, Victor, Macmillan, Alex, Cranfield, Charles G., Sunde, Margaret, Whan, Renee, Graham, Robert M., Martinac, Boris
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726259/ https://www.ncbi.nlm.nih.gov/pubmed/26785754 http://dx.doi.org/10.1038/srep19352

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