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Identification of novel noncoding transcripts in telomerase-negative yeast using RNA-seq
Telomerase is a ribonucleoprotein that maintains the ends of linear chromosomes in most eukaryotes. Loss of telomerase activity results in shortening of telomeric DNA and eventually a specific G2/M cell-cycle arrest known as senescence. In humans, telomere shortening occurs during aging, while inapp...
Autores principales: | Niederer, Rachel O., Papadopoulos, Nickolas, Zappulla, David C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726298/ https://www.ncbi.nlm.nih.gov/pubmed/26786024 http://dx.doi.org/10.1038/srep19376 |
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