Cargando…

Membrane omega-3 fatty acids modulate the oligomerisation kinetics of adenosine A(2A) and dopamine D(2) receptors

Membrane levels of docosahexaenoic acid (DHA), an essential omega-3 polyunsaturated fatty acid (ω-3 PUFA), are decreased in common neuropsychiatric disorders. DHA modulates key cell membrane properties like fluidity, thereby affecting the behaviour of transmembrane proteins like G protein-coupled re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guixà-González, Ramon, Javanainen, Matti, Gómez-Soler, Maricel, Cordobilla, Begoña, Domingo, Joan Carles, Sanz, Ferran, Pastor, Manuel, Ciruela, Francisco, Martinez-Seara, Hector, Selent, Jana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726318/ https://www.ncbi.nlm.nih.gov/pubmed/26796668 http://dx.doi.org/10.1038/srep19839

Ejemplares similares

Triglyceride Form of Docosahexaenoic Acid Mediates Neuroprotection in Experimental Parkinsonism
por: Gómez-Soler, Maricel, et al.
Publicado: (2018)

Erythrocyte Omega-3 Fatty Acid Content in Elite Athletes in Response to Omega-3 Supplementation: A Dose-Response Pilot Study
por: Drobnic, Franchek, et al.
Publicado: (2017)

Revealing Adenosine A(2A)-Dopamine D(2) Receptor Heteromers in Parkinson’s Disease Post-Mortem Brain through a New AlphaScreen-Based Assay
por: Fernández-Dueñas, Víctor, et al.
Publicado: (2019)

Untangling dopamine-adenosine receptor-receptor assembly in experimental parkinsonism in rats
por: Fernández-Dueñas, Víctor, et al.
Publicado: (2015)

Synthesis and Characterization of a New Bivalent Ligand Combining Caffeine and Docosahexaenoic Acid
por: Fernández-Dueñas, Víctor, et al.
Publicado: (2017)

Reduced level of docosahexaenoic acid shifts GPCR neuroreceptors to less ordered membrane regions
por: Javanainen, Matti, et al.
Publicado: (2019)

Membrane cholesterol access into a G-protein-coupled receptor
por: Guixà-González, Ramon, et al.
Publicado: (2017)

Decreased striatal adenosine A(2A)-dopamine D(2) receptor heteromerization in schizophrenia
por: Valle-León, Marta, et al.
Publicado: (2020)

Adenosine A(2A)-dopamine D(2) receptor heteromers operate striatal function: impact on Parkinson's disease pharmacotherapeutics
por: Fernández-Dueñas, Víctor, et al.
Publicado: (2018)

Uncovering Caffeine’s Adenosine A(2A) Receptor Inverse Agonism in Experimental Parkinsonism
por: Fernández-Dueñas, Víctor, et al.
Publicado: (2014)

Transporter oligomerisation: roles in structure and function
por: Cecchetti, Cristina, et al.
Publicado: (2019)

Inadequate Content of Docosahexaenoic Acid (DHA) of Donor Human Milk for Feeding Preterm Infants: A Comparison with Mother’s Own Milk at Different Stages of Lactation
por: Castillo, Félix, et al.
Publicado: (2021)

Diphosphorus Release and Heterocumulene Oligomerisation by Nickel Complexes
por: Hierlmeier, Gabriele, et al.
Publicado: (2022)

OXA-66 structure and oligomerisation of OXAAb enzymes
por: Takebayashi, Yuiko, et al.
Publicado: (2022)

Excessive aggregation of membrane proteins in the Martini model
por: Javanainen, Matti, et al.
Publicado: (2017)

Nanoscale Membrane Domain Formation Driven by Cholesterol
por: Javanainen, Matti, et al.
Publicado: (2017)

Induced Effects of Sodium Ions on Dopaminergic G-Protein Coupled Receptors
por: Selent, Jana, et al.
Publicado: (2010)

A Dynamic View of Molecular Switch Behavior at Serotonin Receptors: Implications for Functional Selectivity
por: Martí-Solano, Maria, et al.
Publicado: (2014)

Oligomerisation of Synaptobrevin-2 Studied by Native Mass Spectrometry and Chemical Cross-Linking
por: Wittig, Sabine, et al.
Publicado: (2018)

Fractal dimension as a measure of surface roughness of G protein-coupled receptors: implications for structure and function
por: Kaczor, Agnieszka A., et al.
Publicado: (2012)

SCoV2-MD: a database for the dynamics of the SARS-CoV-2 proteome and variant impact predictions
por: Torrens-Fontanals, Mariona, et al.
Publicado: (2021)

Yeast-based screen for inhibitors of Aβ oligomerisation
Publicado: (2011)

Emerin oligomerisation properties, impact on lamin and actin recognition
por: Herrada, Isaline, et al.
Publicado: (2015)

Functional and Neuroprotective Role of Striatal Adenosine A(2A) Receptor Heterotetramers
por: Ferré, Sergi, et al.
Publicado: (2019)

RANK receptor oligomerisation in the regulation of NFκB signalling
por: Das, S, et al.
Publicado: (2014)

Probing Bunyavirus N protein oligomerisation using mass spectrometry
por: Shepherd, Dale A, et al.
Publicado: (2014)

Homo-Oligomerisation in Signal Transduction: Dynamics, Homeostasis, Ultrasensitivity, Bistability
por: Koch, Daniel
Publicado: (2020)

Implication of the Transmembrane Domain in the Interleukin 10 Receptor Platform Oligomerisation
por: Kuntzel, Thomas, et al.
Publicado: (2023)

Erythrocyte Membrane Docosahexaenoic Acid (DHA) and Lipid Profile in Preterm Infants at Birth and Over the First Month of Life: A Comparative Study with Infants at Term
por: Castillo Salinas, Félix, et al.
Publicado: (2022)

Special Issue: Adenosine Receptors
por: Ciruela, Francisco, et al.
Publicado: (2017)

The homo-oligomerisation of both Sas-6 and Ana2 is required for efficient centriole assembly in flies
por: Cottee, Matthew A, et al.
Publicado: (2015)

Ligand with Two Modes of Interaction with the Dopamine D(2) Receptor–An Induced-Fit Mechanism of Insurmountable Antagonism
por: Ågren, Richard, et al.
Publicado: (2020)

Fluctuation-based imaging of nuclear Rac1 activation by protein oligomerisation
por: Hinde, Elizabeth, et al.
Publicado: (2014)

Phospho-dependent Regulation of SAMHD1 Oligomerisation Couples Catalysis and Restriction
por: Arnold, Laurence H., et al.
Publicado: (2015)

Studies of the oligomerisation mechanism of a cystatin-based engineered protein scaffold
por: Zalar, Matja, et al.
Publicado: (2019)

Control of glutamate release by complexes of adenosine and cannabinoid receptors
por: Köfalvi, Attila, et al.
Publicado: (2020)

Does Coenzyme Q10 Plus Selenium Supplementation Ameliorate Clinical Outcomes by Modulating Oxidative Stress and Inflammation in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome?
por: Castro-Marrero, Jesús, et al.
Publicado: (2022)

Nonconverged Constraints Cause Artificial Temperature Gradients in Lipid Bilayer Simulations
por: Thallmair, Sebastian, et al.
Publicado: (2021)

Influence of PAS Domain Flanking Regions on Oligomerisation and Redox Signalling By NifL
por: Little, Richard, et al.
Publicado: (2012)

Conservation of DNA-binding specificity and oligomerisation properties within the p53 family
por: Brandt, Tobias, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_fai1mcbbnaotpr6kqlue9vcs20