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Millimeter-wave sensor based on a λ/2-line resonator for identification and dielectric characterization of non-ionic surfactants
Studies of biological and artificial membrane systems, such as niosomes, currently rely on the use of fluorescent tags, which can influence the system under investigation. For this reason, the development of label-free, non-invasive detection techniques is of great interest. We demonstrate an open-v...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726352/ https://www.ncbi.nlm.nih.gov/pubmed/26786983 http://dx.doi.org/10.1038/srep19523 |
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author | Rodilla, H. Kim, A. A. Jeffries, G. D. M. Vukusic, J. Jesorka, A. Stake, J. |
author_facet | Rodilla, H. Kim, A. A. Jeffries, G. D. M. Vukusic, J. Jesorka, A. Stake, J. |
author_sort | Rodilla, H. |
collection | PubMed |
description | Studies of biological and artificial membrane systems, such as niosomes, currently rely on the use of fluorescent tags, which can influence the system under investigation. For this reason, the development of label-free, non-invasive detection techniques is of great interest. We demonstrate an open-volume label-free millimeter-wave sensing platform based on a coplanar waveguide, developed for identification and characterization of niosome constituents. A design based on a λ/2-line resonator was used and on-wafer measurements of transmission and reflection parameters were performed up to 110 GHz. Our sensor was able to clearly distinguish between common niosome constituents, non-ionic surfactants Tween 20 and Span 80, measuring a resonance shift of 3 GHz between them. The complex permittivities of the molecular compounds have been extracted. Our results indicate insignificant frequency dependence in the investigated frequency range (3 GHz – 110 GHz). Values of permittivity around 3.0 + 0.7i and 2.2 + 0.4i were obtained for Tween 20 and Span 80, respectively. |
format | Online Article Text |
id | pubmed-4726352 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-47263522016-01-27 Millimeter-wave sensor based on a λ/2-line resonator for identification and dielectric characterization of non-ionic surfactants Rodilla, H. Kim, A. A. Jeffries, G. D. M. Vukusic, J. Jesorka, A. Stake, J. Sci Rep Article Studies of biological and artificial membrane systems, such as niosomes, currently rely on the use of fluorescent tags, which can influence the system under investigation. For this reason, the development of label-free, non-invasive detection techniques is of great interest. We demonstrate an open-volume label-free millimeter-wave sensing platform based on a coplanar waveguide, developed for identification and characterization of niosome constituents. A design based on a λ/2-line resonator was used and on-wafer measurements of transmission and reflection parameters were performed up to 110 GHz. Our sensor was able to clearly distinguish between common niosome constituents, non-ionic surfactants Tween 20 and Span 80, measuring a resonance shift of 3 GHz between them. The complex permittivities of the molecular compounds have been extracted. Our results indicate insignificant frequency dependence in the investigated frequency range (3 GHz – 110 GHz). Values of permittivity around 3.0 + 0.7i and 2.2 + 0.4i were obtained for Tween 20 and Span 80, respectively. Nature Publishing Group 2016-01-20 /pmc/articles/PMC4726352/ /pubmed/26786983 http://dx.doi.org/10.1038/srep19523 Text en Copyright © 2016, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article Rodilla, H. Kim, A. A. Jeffries, G. D. M. Vukusic, J. Jesorka, A. Stake, J. Millimeter-wave sensor based on a λ/2-line resonator for identification and dielectric characterization of non-ionic surfactants |
title | Millimeter-wave sensor based on a λ/2-line resonator for identification and dielectric characterization of non-ionic surfactants |
title_full | Millimeter-wave sensor based on a λ/2-line resonator for identification and dielectric characterization of non-ionic surfactants |
title_fullStr | Millimeter-wave sensor based on a λ/2-line resonator for identification and dielectric characterization of non-ionic surfactants |
title_full_unstemmed | Millimeter-wave sensor based on a λ/2-line resonator for identification and dielectric characterization of non-ionic surfactants |
title_short | Millimeter-wave sensor based on a λ/2-line resonator for identification and dielectric characterization of non-ionic surfactants |
title_sort | millimeter-wave sensor based on a λ/2-line resonator for identification and dielectric characterization of non-ionic surfactants |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726352/ https://www.ncbi.nlm.nih.gov/pubmed/26786983 http://dx.doi.org/10.1038/srep19523 |
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