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Association of DNA Methylation at CPT1A Locus with Metabolic Syndrome in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) Study

In this study, we conducted an epigenome-wide association study of metabolic syndrome (MetS) among 846 participants of European descent in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN). DNA was isolated from CD4+ T cells and methylation at ~470,000 cytosine-phosphate-guanine dinucleo...

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Detalles Bibliográficos
Autores principales: Das, Mithun, Sha, Jin, Hidalgo, Bertha, Aslibekyan, Stella, Do, Anh N., Zhi, Degui, Sun, Dianjianyi, Zhang, Tao, Li, Shengxu, Chen, Wei, Srinivasan, Sathanur R., Tiwari, Hemant K., Absher, Devin, Ordovas, Jose M., Berenson, Gerald S., Arnett, Donna K., Irvin, Marguerite R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726462/
https://www.ncbi.nlm.nih.gov/pubmed/26808626
http://dx.doi.org/10.1371/journal.pone.0145789