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Transcriptomic Determinants of Scrapie Prion Propagation in Cultured Ovine Microglia

Susceptibility to infection by prions is highly dependent on the amino acid sequence and host expression of the cellular prion protein (PrP(C)); however, cellular expression of a genetically susceptible PrP(C) is insufficient. As an example, it has been shown in cultured cells that permissive and re...

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Detalles Bibliográficos
Autores principales:	Muñoz-Gutiérrez, Juan F., Aguilar Pierlé, Sebastián, Schneider, David A., Baszler, Timothy V., Stanton, James B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726464/ https://www.ncbi.nlm.nih.gov/pubmed/26807844 http://dx.doi.org/10.1371/journal.pone.0147727

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