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Post-transcriptional Control of Tumor Cell Autonomous Metastatic Potential by CCR4-NOT Deadenylase CNOT7
Accumulating evidence supports the role of an aberrant transcriptome as a driver of metastatic potential. Deadenylation is a general regulatory node for post-transcriptional control by microRNAs and other determinants of RNA stability. Previously, we demonstrated that the CCR4-NOT scaffold component...
Autores principales: | Faraji, Farhoud, Hu, Ying, Yang, Howard H., Lee, Maxwell P., Winkler, G. Sebastian, Hafner, Markus, Hunter, Kent W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726497/ https://www.ncbi.nlm.nih.gov/pubmed/26807845 http://dx.doi.org/10.1371/journal.pgen.1005820 |
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