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A Comprehensive Behavioral Test Battery to Assess Learning and Memory in 129S6/Tg2576 Mice

Transgenic Tg2576 mice overexpressing human amyloid precursor protein (hAPP) are a widely used Alzheimer’s disease (AD) mouse model to evaluate treatment effects on amyloid beta (Aβ) pathology and cognition. Tg2576 mice on a B6;SJL background strain carry a recessive rd1 mutation that leads to early...

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Detalles Bibliográficos
Autores principales:	Wolf, Andrea, Bauer, Björn, Abner, Erin L., Ashkenazy-Frolinger, Tal, Hartz, Anika M. S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726499/ https://www.ncbi.nlm.nih.gov/pubmed/26808326 http://dx.doi.org/10.1371/journal.pone.0147733

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