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Glucose Uptake Activities of Bis (2, 3-Dibromo-4, 5-Dihydroxybenzyl) Ether, a Novel Marine Natural Product from Red Alga Odonthaliacorymbifera with Protein Tyrosine Phosphatase 1B Inhibition, In Vitro and In Vivo

BACKGROUND AND AIMS: Protein tyrosine phosphatase 1B (PTP1B) is a novel therapeutic target for type-2 diabetes, which negatively regulates the insulin signaling transduction. Bis (2, 3-dibromo-4, 5-dihydroxybenzyl) ether (BDDE), a novel bromophenol isolated from the Red Alga, is a novel PTP1B inhibi...

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Detalles Bibliográficos
Autores principales:	Xu, Feng, Wang, Fang, Wang, Zhenhong, Lv, Wenshan, Wang, Wei, Wang, Yangang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726511/ https://www.ncbi.nlm.nih.gov/pubmed/26808535 http://dx.doi.org/10.1371/journal.pone.0147748

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