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Hepatic Deficiency of Augmenter of Liver Regeneration Exacerbates Alcohol-Induced Liver Injury and Promotes Fibrosis in Mice

Why only a subpopulation (about 15%) of humans develops liver cirrhosis due to alcohol is a critical as yet unanswered question. Liver-specific depletion of augmenter of liver regeneration (ALR) protein in mice causes robust steatosis and hepatocyte apoptosis by 2 weeks; these pathologies regress su...

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Detalles Bibliográficos
Autores principales:	Kumar, Sudhir, Wang, Jiang, Rani, Richa, Gandhi, Chandrashekhar R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726524/ https://www.ncbi.nlm.nih.gov/pubmed/26808690 http://dx.doi.org/10.1371/journal.pone.0147864

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