Cigarette Smoke Disturbs the Survival of CD8(+) Tc/Tregs Partially through Muscarinic Receptors-Dependent Mechanisms in Chronic Obstructive Pulmonary Disease

BACKGROUND: CD8(+) T cells (Cytotoxic T cells, Tc) are known to play a critical role in the pathogenesis of smoking related airway inflammation including chronic obstructive pulmonary disease (COPD). However, how cigarette smoke directly impacts systematic CD8(+) T cell and regulatory T cell (Treg)...

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Detalles Bibliográficos
Autores principales: Chen, Gang, Zhou, Mei, Chen, Long, Meng, Zhao-Ji, Xiong, Xian-Zhi, Liu, Hong-Ju, Xin, Jian-Bao, Zhang, Jian-Chu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726532/
https://www.ncbi.nlm.nih.gov/pubmed/26808506
http://dx.doi.org/10.1371/journal.pone.0147232

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