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Deletion of ASK1 Protects against Hyperoxia-Induced Acute Lung Injury
Apoptosis signal-regulating kinase 1 (ASK1), a member of the MAPK kinase kinase kinase (MAP3K) family, is activated by various stimuli, which include oxidative stress, endoplasmic reticulum (ER) stress, calcium influx, DNA damage-inducing agents and receptor-mediated signaling through tumor necrosis...
Autores principales: | Fukumoto, Jutaro, Cox, Ruan, Fukumoto, Itsuko, Cho, Young, Parthasarathy, Prasanna Tamarapu, Galam, Lakshmi, Lockey, Richard F., Kolliputi, Narasaiah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726536/ https://www.ncbi.nlm.nih.gov/pubmed/26807721 http://dx.doi.org/10.1371/journal.pone.0147652 |
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