Cargando…

Novel Neuroprotective Multicomponent Therapy for Amyotrophic Lateral Sclerosis Designed by Networked Systems

Amyotrophic Lateral Sclerosis is a fatal, progressive neurodegenerative disease characterized by loss of motor neuron function for which there is no effective treatment. One of the main difficulties in developing new therapies lies on the multiple events that contribute to motor neuron death in amyo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Herrando-Grabulosa, Mireia, Mulet, Roger, Pujol, Albert, Mas, José Manuel, Navarro, Xavier, Aloy, Patrick, Coma, Mireia, Casas, Caty
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726541/ https://www.ncbi.nlm.nih.gov/pubmed/26807587 http://dx.doi.org/10.1371/journal.pone.0147626

Ejemplares similares

Early presymptomatic cholinergic dysfunction in a murine model of amyotrophic lateral sclerosis
por: Casas, Caty, et al.
Publicado: (2013)

Early presymptomatic cholinergic dysfunction in a murine model of amyotrophic lateral sclerosis
por: Casas, Caty, et al.
Publicado: (2013)

Sensory Involvement in Amyotrophic Lateral Sclerosis
por: Rubio, Miguel A., et al.
Publicado: (2022)

Neuroprotective Drug for Nerve Trauma Revealed Using Artificial Intelligence
por: Romeo-Guitart, David, et al.
Publicado: (2018)

Network-based proteomic approaches reveal the neurodegenerative, neuroprotective and pain-related mechanisms involved after retrograde axonal damage
por: Casas, Caty, et al.
Publicado: (2015)

Neurotrophic Properties of C-Terminal Domain of the Heavy Chain of Tetanus Toxin on Motor Neuron Disease
por: Herrando-Grabulosa, Mireia, et al.
Publicado: (2020)

ATG5 overexpression is neuroprotective and attenuates cytoskeletal and vesicle-trafficking alterations in axotomized motoneurons
por: Leiva-Rodríguez, Tatiana, et al.
Publicado: (2018)

Sigma-1 Receptor is a Pharmacological Target to Promote Neuroprotection in the SOD1(G93A) ALS Mice
por: Gaja-Capdevila, Núria, et al.
Publicado: (2021)

Neuroprotective Effects of Sigma 1 Receptor Ligands on Motoneuron Death after Spinal Root Injury in Mice
por: Gaja-Capdevila, Núria, et al.
Publicado: (2021)

Neuregulin 1 Reduces Motoneuron Cell Death and Promotes Neurite Growth in an in Vitro Model of Motoneuron Degeneration
por: Mòdol-Caballero, Guillem, et al.
Publicado: (2018)

GRP78 Overexpression Triggers PINK1-IP(3)R-Mediated Neuroprotective Mitophagy
por: Leiva-Rodríguez, Tatiana, et al.
Publicado: (2021)

EST79232 and EST79376, Two Novel Sigma-1 Receptor Ligands, Exert Neuroprotection on Models of Motoneuron Degeneration
por: Gaja-Capdevila, Núria, et al.
Publicado: (2022)

Characterization of somatosensory neuron involvement in the SOD1(G93A) mouse model
por: Rubio, Miguel A., et al.
Publicado: (2022)

TDP-43 Cytoplasmic Translocation in the Skin Fibroblasts of ALS Patients
por: Rubio, Miguel A., et al.
Publicado: (2022)

Revealing the molecular relationship between type 2 diabetes and the metabolic changes induced by a very-low-carbohydrate low-fat ketogenic diet
por: Farrés, Judith, et al.
Publicado: (2010)

Mechanisms of Neuroprotection by Protein Disulphide Isomerase in Amyotrophic Lateral Sclerosis
por: Walker, Adam K., et al.
Publicado: (2011)

The potential of GPNMB as novel neuroprotective factor in amyotrophic lateral sclerosis
por: Tanaka, Hirotaka, et al.
Publicado: (2012)

Could Conservative Iron Chelation Lead to Neuroprotection in Amyotrophic Lateral Sclerosis?
por: Moreau, Caroline, et al.
Publicado: (2018)

Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis
por: Muzio, Luca, et al.
Publicado: (2020)

Neuroprotective effects of violacein in a model of inherited amyotrophic lateral sclerosis
por: Olivera-Bravo, Silvia, et al.
Publicado: (2022)

Neuroprotective Effect of Non-viral Gene Therapy Treatment Based on Tetanus Toxin C-fragment in a Severe Mouse Model of Spinal Muscular Atrophy
por: Oliván, Sara, et al.
Publicado: (2016)

Autologous bone marrow mononuclear cells as neuroprotective treatment of amyotrophic lateral sclerosis
por: Ruiz-López, Francisco José, et al.
Publicado: (2016)

Amyotrophic lateral sclerosis
por: Wijesekera, Lokesh C, et al.
Publicado: (2009)

Methods for diagnosing perceived age on the basis of an ensemble of phenotypic features
por: Coma, Mireia, et al.
Publicado: (2014)

The neuroprotective effects of human growth hormone as a potential treatment for amyotrophic lateral sclerosis
por: Chung, Jin-Young, et al.
Publicado: (2015)

GRP78 at the Centre of the Stage in Cancer and Neuroprotection
por: Casas, Caty
Publicado: (2017)

Skeletal muscle in amyotrophic lateral sclerosis
por: Shefner, Jeremy M, et al.
Publicado: (2023)

Non-invasive ventilation in amyotrophic lateral sclerosis
por: Dorst, Johannes, et al.
Publicado: (2019)

Gene Therapy Overexpressing Neuregulin 1 Type I in Combination With Neuregulin 1 Type III Promotes Functional Improvement in the SOD1(G93A) ALS Mice
por: Mòdol-Caballero, Guillem, et al.
Publicado: (2021)

Amyotrophic lateral sclerosis and neuroregeneration
Publicado: (2012)

Mimickers of Amyotrophic Lateral Sclerosis
por: Dubey, Ayush, et al.
Publicado: (2019)

Destination Amyotrophic Lateral Sclerosis
por: Keon, Matt, et al.
Publicado: (2021)

Prionoids in amyotrophic lateral sclerosis
por: Gosset, Philippe, et al.
Publicado: (2022)

Amyotrophic lateral sclerosis and cerebellum
por: Kabiljo, Renata, et al.
Publicado: (2022)

Dysautonomia in Amyotrophic Lateral Sclerosis
por: Oprisan, Alexandra L., et al.
Publicado: (2023)

Adaptive Immune Neuroprotection in G93A-SOD1 Amyotrophic Lateral Sclerosis Mice
por: Banerjee, Rebecca, et al.
Publicado: (2008)

Monocarboxylate transporter functions and neuroprotective effects of valproic acid in experimental models of amyotrophic lateral sclerosis
por: Gyawali, Asmita, et al.
Publicado: (2022)

Effects of the Edaravone, a Drug Approved for the Treatment of Amyotrophic Lateral Sclerosis, on Mitochondrial Function and Neuroprotection
por: Cha, Sun Joo, et al.
Publicado: (2022)

Saccadic intrusions in amyotrophic lateral sclerosis (ALS)
por: Becker, Wolfgang, et al.
Publicado: (2019)

The Proton-Pump Inhibitor Lansoprazole Enhances Amyloid Beta Production
por: Badiola, Nahuai, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_agpurlnk3h1i92g4cqq8qpltpa