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RUNX1B Expression Is Highly Heterogeneous and Distinguishes Megakaryocytic and Erythroid Lineage Fate in Adult Mouse Hematopoiesis

The Core Binding Factor (CBF) protein RUNX1 is a master regulator of definitive hematopoiesis, crucial for hematopoietic stem cell (HSC) emergence during ontogeny. RUNX1 also plays vital roles in adult mice, in regulating the correct specification of numerous blood lineages. Akin to the other mammal...

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Detalles Bibliográficos
Autores principales:	Draper, Julia E., Sroczynska, Patrycja, Tsoulaki, Olga, Leong, Hui Sun, Fadlullah, Muhammad Z. H., Miller, Crispin, Kouskoff, Valerie, Lacaud, Georges
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726605/ https://www.ncbi.nlm.nih.gov/pubmed/26808730 http://dx.doi.org/10.1371/journal.pgen.1005814

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