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Brugia malayi Antigen (BmA) Inhibits HIV-1 Trans-Infection but Neither BmA nor ES-62 Alter HIV-1 Infectivity of DC Induced CD4(+) Th-Cells

One of the hallmarks of HIV-1 disease is the association of heightened CD4(+) T-cell activation with HIV-1 replication. Parasitic helminths including filarial nematodes have evolved numerous and complex mechanisms to skew, dampen and evade human immune responses suggesting that HIV-1 infection may b...

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Detalles Bibliográficos
Autores principales: Mouser, Emily E. I. M., Pollakis, Georgios, Yazdanbakhsh, Maria, Harnett, William, de Jong, Esther C., Paxton, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726616/
https://www.ncbi.nlm.nih.gov/pubmed/26808476
http://dx.doi.org/10.1371/journal.pone.0146527