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Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study

Recent work identified a high prevalence of modifiable risk factors for cardiovascular disease (CVD) among urban black South Africans. The aim was to track the progression of CVD risk factors in a multi-ethnic sample of South Africans. Participants were 173 black (aged 47.5 ± 7.8 yrs) and 186 white...

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Autores principales: Hamer, Mark, von Känel, Roland, Reimann, Manja, Malan, Nico T., Schutte, Alta E., Huisman, Hugo W., Malan, Leone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726657/
https://www.ncbi.nlm.nih.gov/pubmed/25437890
http://dx.doi.org/10.1016/j.atherosclerosis.2014.11.019
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author Hamer, Mark
von Känel, Roland
Reimann, Manja
Malan, Nico T.
Schutte, Alta E.
Huisman, Hugo W.
Malan, Leone
author_facet Hamer, Mark
von Känel, Roland
Reimann, Manja
Malan, Nico T.
Schutte, Alta E.
Huisman, Hugo W.
Malan, Leone
author_sort Hamer, Mark
collection PubMed
description Recent work identified a high prevalence of modifiable risk factors for cardiovascular disease (CVD) among urban black South Africans. The aim was to track the progression of CVD risk factors in a multi-ethnic sample of South Africans. Participants were 173 black (aged 47.5 ± 7.8 yrs) and 186 white teachers (aged 49.6 ± 9.9 yrs) that were examined at baseline and 3 years follow-up. Blacks demonstrated a substantially higher prevalence of composite CVD burden (defined as history of physician diagnosed heart disease, use of anti-hypertensives, anti-diabetic, or statin medications at either time point) compared to whites (49.1 vs. 32.0%, p = 0.012) respectively. After controlling for baseline, the black participants demonstrated greater increases in 24 h systolic and diastolic blood pressure, total cholesterol, fasting glucose, fibrinogen, D-dimer, and waist circumference in comparison with whites. In summary, an adverse progression of CVD risk factors was observed in the whole sample, although to a larger degree in black participants. Aggressive treatment strategies for controlling risk factors in black Africans are needed to reduce the increasing burden of CVD in South Africa.
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spelling pubmed-47266572016-02-22 Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study Hamer, Mark von Känel, Roland Reimann, Manja Malan, Nico T. Schutte, Alta E. Huisman, Hugo W. Malan, Leone Atherosclerosis Article Recent work identified a high prevalence of modifiable risk factors for cardiovascular disease (CVD) among urban black South Africans. The aim was to track the progression of CVD risk factors in a multi-ethnic sample of South Africans. Participants were 173 black (aged 47.5 ± 7.8 yrs) and 186 white teachers (aged 49.6 ± 9.9 yrs) that were examined at baseline and 3 years follow-up. Blacks demonstrated a substantially higher prevalence of composite CVD burden (defined as history of physician diagnosed heart disease, use of anti-hypertensives, anti-diabetic, or statin medications at either time point) compared to whites (49.1 vs. 32.0%, p = 0.012) respectively. After controlling for baseline, the black participants demonstrated greater increases in 24 h systolic and diastolic blood pressure, total cholesterol, fasting glucose, fibrinogen, D-dimer, and waist circumference in comparison with whites. In summary, an adverse progression of CVD risk factors was observed in the whole sample, although to a larger degree in black participants. Aggressive treatment strategies for controlling risk factors in black Africans are needed to reduce the increasing burden of CVD in South Africa. Elsevier 2015-01 /pmc/articles/PMC4726657/ /pubmed/25437890 http://dx.doi.org/10.1016/j.atherosclerosis.2014.11.019 Text en © 2014 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hamer, Mark
von Känel, Roland
Reimann, Manja
Malan, Nico T.
Schutte, Alta E.
Huisman, Hugo W.
Malan, Leone
Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study
title Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study
title_full Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study
title_fullStr Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study
title_full_unstemmed Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study
title_short Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study
title_sort progression of cardiovascular risk factors in black africans: 3 year follow up of the sabpa cohort study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726657/
https://www.ncbi.nlm.nih.gov/pubmed/25437890
http://dx.doi.org/10.1016/j.atherosclerosis.2014.11.019
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