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Plasticity of empty major histocompatibility complex class I molecules determines peptide-selector function

Major histocompatibility complex class I (MHC I) proteins provide protection from intracellular pathogens and cancer via each of a cell's MHC I molecules binding and presenting a peptide to cytotoxic T lymphocytes. MHC I genes are highly polymorphic and can have significant diversity, with poly...

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Detalles Bibliográficos
Autores principales: van Hateren, Andy, Bailey, Alistair, Werner, Jörn M., Elliott, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726658/
https://www.ncbi.nlm.nih.gov/pubmed/25818313
http://dx.doi.org/10.1016/j.molimm.2015.03.010