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E2F/Rb Family Proteins Mediate Interferon Induced Repression of Adenovirus Immediate Early Transcription to Promote Persistent Viral Infection

Interferons (IFNs) are cytokines that have pleiotropic effects and play important roles in innate and adaptive immunity. IFNs have broad antiviral properties and function by different mechanisms. IFNs fail to inhibit wild-type Adenovirus (Ad) replication in established cancer cell lines. In this stu...

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Detalles Bibliográficos
Autores principales: Zheng, Yueting, Stamminger, Thomas, Hearing, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726734/
https://www.ncbi.nlm.nih.gov/pubmed/26809031
http://dx.doi.org/10.1371/journal.ppat.1005415