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Coenzyme Q Biosynthesis: Evidence for a Substrate Access Channel in the FAD-Dependent Monooxygenase Coq6

Coq6 is an enzyme involved in the biosynthesis of coenzyme Q, a polyisoprenylated benzoquinone lipid essential to the function of the mitochondrial respiratory chain. In the yeast Saccharomyces cerevisiae, this putative flavin-dependent monooxygenase is proposed to hydroxylate the benzene ring of co...

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Detalles Bibliográficos
Autores principales:	Ismail, Alexandre, Leroux, Vincent, Smadja, Myriam, Gonzalez, Lucie, Lombard, Murielle, Pierrel, Fabien, Mellot-Draznieks, Caroline, Fontecave, Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726752/ https://www.ncbi.nlm.nih.gov/pubmed/26808124 http://dx.doi.org/10.1371/journal.pcbi.1004690

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