Cargando…

Characterization of Heterogeneous Prostate Tumors in Targeted Pten Knockout Mice

Previously, we generated a preclinical mouse prostate tumor model based on PSA-Cre driven inactivation of Pten. In this model homogeneous hyperplastic prostates (4-5m) developed at older age (>10m) into tumors. Here, we describe the molecular and histological characterization of the tumors in ord...

Descripción completa

Detalles Bibliográficos
Autores principales:	Korsten, Hanneke, Ziel-van der Made, Angelique C. J., van Weerden, Wytske M., van der Kwast, Theo, Trapman, Jan, Van Duijn, Petra W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726760/ https://www.ncbi.nlm.nih.gov/pubmed/26807730 http://dx.doi.org/10.1371/journal.pone.0147500

Ejemplares similares

Accumulating Progenitor Cells in the Luminal Epithelial Cell Layer Are Candidate Tumor Initiating Cells in a Pten Knockout Mouse Prostate Cancer Model
por: Korsten, Hanneke, et al.
Publicado: (2009)

E17K substitution in AKT1 in prostate cancer
por: Boormans, J L, et al.
Publicado: (2010)

Overexpression of Full-Length ETV1 Transcripts in Clinical Prostate Cancer Due to Gene Translocation
por: Gasi, Delila, et al.
Publicado: (2011)

Patient-Derived Xenograft Models in Cancer Research
por: van Weerden, Wytske M.
Publicado: (2021)

Noise: sources, characterization, measurement
por: Van der Ziel, A
Publicado: (1970)

Role of the DNA damage response in prostate cancer formation, progression and treatment
por: Zhang, Wenhao, et al.
Publicado: (2019)

Correction to: Role of the DNA damage response in prostate cancer formation, progression and treatment
por: Zhang, Wenhao, et al.
Publicado: (2019)

On cribriform prostate cancer
por: Kweldam, Charlotte F., et al.
Publicado: (2018)

Suspicious findings on micro-ultrasound imaging and early detection of prostate cancer
por: Ghai, Sangeet, et al.
Publicado: (2017)

Grading of prostate cancer: a work in progress
por: Kweldam, C F, et al.
Publicado: (2018)

Cell Line Characteristics Predict Subsequent Resistance to Androgen Receptor-Targeted Agents (ARTA) in Preclinical Models of Prostate Cancer
por: Moll, Jan Matthijs, et al.
Publicado: (2022)

Variations in activin receptor, inhibin/activin subunit and follistatin mRNAs in human prostate tumour tissues
por: Schaik, R H N van, et al.
Publicado: (2000)

Modeling Prostate Cancer Treatment Responses in the Organoid Era: 3D Environment Impacts Drug Testing
por: Van Hemelryk, Annelies, et al.
Publicado: (2021)

Predicting biochemical recurrence and prostate cancer‐specific mortality after radical prostatectomy: comparison of six prediction models in a cohort of patients with screening‐ and clinically detected prostate cancer
por: Remmers, Sebastiaan, et al.
Publicado: (2019)

Solid state physical electronics
por: Van der Ziel, Albert
Publicado: (1968)

Nonlinear electronic circuits
por: Van der Ziel, A
Publicado: (1977)

Noise in measurements
por: Van der Ziel, A
Publicado: (1976)

Bypass Mechanisms of the Androgen Receptor Pathway in Therapy-Resistant Prostate Cancer Cell Models
por: Marques, Rute B., et al.
Publicado: (2010)

A reported 20-gene expression signature to predict lymph node-positive disease at radical cystectomy for muscle-invasive bladder cancer is clinically not applicable
por: van Kessel, Kim E. M., et al.
Publicado: (2017)

Modulation of Androgen Receptor Signaling in Hormonal Therapy-Resistant Prostate Cancer Cell Lines
por: Marques, Rute B., et al.
Publicado: (2011)

Apalutamide Sensitizes Prostate Cancer to Ionizing Radiation via Inhibition of Non-Homologous End-Joining DNA Repair
por: Zhang, Wenhao, et al.
Publicado: (2019)

Electrónica física del estado sólido /
por: Van der Ziel, Aldert, 1910-
Publicado: (1972)

Proteomic and transcriptomic profiling of Pten gene‐knockout mouse model of prostate cancer
por: Zhang, Jinhui, et al.
Publicado: (2020)

A Novel Controlled PTEN-Knockout Mouse Model for Prostate Cancer Study
por: Liu, Sen, et al.
Publicado: (2021)

Testosterone Diminishes Cabazitaxel Efficacy and Intratumoral Accumulation in a Prostate Cancer Xenograft Model()
por: Mout, Lisanne, et al.
Publicado: (2017)

Nuclear Eg5 (kinesin spindle protein) expression predicts docetaxel response and prostate cancer aggressiveness
por: Wissing, Michel D., et al.
Publicado: (2014)

Engineered Jurkat Cells for Targeting Prostate-Specific Membrane Antigen on Prostate Cancer Cells by Nanobody-Based Chimeric Antigen Receptor
por: Hassani, Mahmoud, et al.
Publicado: (2020)

Prostate Cancer Secretome and Membrane Proteome from Pten Conditional Knockout Mice Identify Potential Biomarkers for Disease Progression
por: Santos, Nilton J., et al.
Publicado: (2022)

Leukocytosis and Enhanced Susceptibility to Endotoxemia but Not Atherosclerosis in Adrenalectomized APOE Knockout Mice
por: Hoekstra, Menno, et al.
Publicado: (2013)

Awe and anxiety for cancer cells: connecting scientists and patients in a holistic approach of metastasis research
por: Bronkhorst, Hildert, et al.
Publicado: (2023)

GRPR versus PSMA: expression profiles during prostate cancer progression demonstrate the added value of GRPR-targeting theranostic approaches
por: Verhoeven, Marjolein, et al.
Publicado: (2023)

Viability Analysis and High-Content Live-Cell Imaging for Drug Testing in Prostate Cancer Xenograft-Derived Organoids
por: Van Hemelryk, Annelies, et al.
Publicado: (2023)

An inducible knockout mouse model for PTEN cancers
Publicado: (2013)

Ex vivo treatment of prostate tumor tissue recapitulates in vivo therapy response
por: Zhang, Wenhao, et al.
Publicado: (2018)

Reovirus mutant jin-3 exhibits lytic and immune-stimulatory effects in preclinical human prostate cancer models
por: van de Merbel, Arjanneke F., et al.
Publicado: (2021)

NS‐Pten knockout mice show sex‐ and age‐specific differences in ultrasonic vocalizations
por: Binder, Matthew S., et al.
Publicado: (2017)

Probiotics suppress nonalcoholic steatohepatitis and carcinogenesis progression in hepatocyte-specific PTEN knockout mice
por: Arai, Naoshi, et al.
Publicado: (2022)

Activation of c-MET Induces a Stem-Like Phenotype in Human Prostate Cancer
por: van Leenders, Geert J. L. H., et al.
Publicado: (2011)

The Future of PSMA-Targeted Radionuclide Therapy: An Overview of Recent Preclinical Research
por: Ruigrok, Eline A.M., et al.
Publicado: (2019)

Leukocyte ABCA1 Remains Atheroprotective in Splenectomized LDL Receptor Knockout Mice
por: Lammers, Bart, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_36tg9ne3vbjr1o0pod83foikk3