Cargando…

Ursodeoxycholic Acid (UDCA) Exerts Anti-Atherogenic Effects by Inhibiting RAGE Signaling in Diabetic Atherosclerosis

A naturally occurring bile acid, ursodeoxycholic acid (UDCA), is known to alleviate endoplasmic reticulum (ER) stress at the cellular level. However, the detailed action mechanisms of UDCA in atherosclerosis are not fully understood. In this study, we demonstrated whether UDCA exerts anti-atherogeni...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chung, Jihwa, An, Shung Hyun, Kang, Sang Won, Kwon, Kihwan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726772/ https://www.ncbi.nlm.nih.gov/pubmed/26807573 http://dx.doi.org/10.1371/journal.pone.0147839

Ejemplares similares

Ursodeoxycholic Acid (UDCA) Exerts Anti-Atherogenic Effects by Inhibiting Endoplasmic Reticulum (ER) Stress Induced by Disturbed Flow
por: Chung, Jihwa, et al.
Publicado: (2015)

Glyceric Prodrug of Ursodeoxycholic Acid (UDCA): Novozym 435-Catalyzed Synthesis of UDCA-Monoglyceride
por: Zappaterra, Federico, et al.
Publicado: (2021)

Discovery of novel peptides targeting pro-atherogenic endothelium in disturbed flow regions -Targeted siRNA delivery to pro-atherogenic endothelium in vivo
por: Chung, Jihwa, et al.
Publicado: (2016)

Latest development in the synthesis of ursodeoxycholic acid (UDCA): a critical review
por: Tonin, Fabio, et al.
Publicado: (2018)

Pretreatment with Ursodeoxycholic Acid (UDCA) as a Novel Pharmacological Intervention in Hepatobiliary Scintigraphy
por: Jeong, Hwan-Jeong, et al.
Publicado: (2005)

Waking Action of Ursodeoxycholic Acid (UDCA) Involves Histamine and GABA(A) Receptor Block
por: Yanovsky, Yevgenij, et al.
Publicado: (2012)

Coxsackievirus and adenovirus receptor mediates the responses of endothelial cells to fluid shear stress
por: Chung, Jihwa, et al.
Publicado: (2019)

Differential effects of norUDCA and UDCA in obstructive cholestasis in mice
por: Fickert, Peter, et al.
Publicado: (2013)

Fluid Shear Stress Regulates the Landscape of microRNAs in Endothelial Cell-Derived Small Extracellular Vesicles and Modulates the Function of Endothelial Cells
por: Chung, Jihwa, et al.
Publicado: (2022)

Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Protect Cardiomyocytes from Doxorubicin-Induced Cardiomyopathy by Upregulating Survivin Expression via the miR-199a-3p-Akt-Sp1/p53 Signaling Pathway
por: Lee, Ji Yoon, et al.
Publicado: (2021)

Combination therapy of fenofibrate and ursodeoxycholic acid in patients with primary biliary cirrhosis who respond incompletely to UDCA monotherapy: a meta-analysis
por: Zhang, Yan, et al.
Publicado: (2015)

Extracorporeal shock waves protect cardiomyocytes from doxorubicin-induced cardiomyopathy by upregulating survivin via the integrin-ILK-Akt-Sp1/p53 axis
por: Yoon Lee, Ji, et al.
Publicado: (2019)

UDCA in UC: A true disease modifier or symptoms reliever?
por: Sulais, Eman Al
Publicado: (2021)

The Atherogenic Role of Circulating Modified Lipids in Atherosclerosis
por: Summerhill, Volha I., et al.
Publicado: (2019)

Dicarbonyl Stress and Atherosclerosis: Is It All RAGE?
por: Muniyappa, Ranganath, et al.
Publicado: (2014)

Repurposing UDCA, an FXR Inhibitor, to Prevent SARS-Cov-2 Infection
por: Prayitno, Khairunnadiya, et al.
Publicado: (2023)

UDCA, a novel strategy for preventing SARS-CoV-2 infection via FXR-mediated ACE2 downregulation: UDCA and SARS-CoV-2 infection
por: Chen, Mengjiao, et al.
Publicado: (2023)

Endothelial Lipase Exerts its Anti-Atherogenic Effect through Increased Catabolism of β-VLDLs
por: Yan, Haizhao, et al.
Publicado: (2021)

Atherogenic Indices Can Predict Atherosclerosis in Patients with Sarcoidosis
por: Selendili, Okan, et al.
Publicado: (2021)

Novel mechanism of gene transfection by low-energy shock wave
por: Hoon Ha, Chang, et al.
Publicado: (2015)

The Effect of Soluble RAGE on Inhibition of Angiotensin II-Mediated Atherosclerosis in Apolipoprotein E Deficient Mice
por: Lee, Dajeong, et al.
Publicado: (2013)

Bivalent Ligand UDCA-LPE Inhibits Pro-Fibrogenic Integrin Signalling by Inducing Lipid Raft-Mediated Internalization
por: Su, Jie, et al.
Publicado: (2018)

Correlation Analysis of CML, sRAGE, and esRAGE and the Measure of Atherosclerosis of Coronary Heart Disease
por: Liu, Wenjun, et al.
Publicado: (2022)

An Interleukin-6 Receptor Antibody Suppresses Atherosclerosis in Atherogenic Mice
por: Akita, Koji, et al.
Publicado: (2017)

Mechanosensitive molecular interactions in atherogenic regions of the arteries: development of atherosclerosis
por: Mishchenko, E.L., et al.
Publicado: (2021)

Atherosclerosis Development and Progression: The Role of Atherogenic Small, Dense LDL
por: Vekic, Jelena, et al.
Publicado: (2022)

Comment on: Atherogenic indices can predict atherosclerosis in patients with sarcoidosis
por: Rizzi, Luigi, et al.
Publicado: (2022)

Retraction: The Effect of Soluble RAGE on Inhibition of Angiotensin II-Mediated Atherosclerosis in Apolipoprotein E Deficient Mice
por: Lee, Dajeong, et al.
Publicado: (2014)

External Validation of UDCA Response Score in Slovak and Croatian Patients with Primary Biliary Cholangitis
por: Gazda, Jakub, et al.
Publicado: (2021)

Gut Microbial Profile Changes in Patients with Gallbladder Stones after UDCA/CDCA Treatment
por: Lee, Jungnam, et al.
Publicado: (2023)

Retracted: Correlation Analysis of CML, sRAGE, and esRAGE and the Measure of Atherosclerosis of Coronary Heart Disease
por: Intelligence and Neuroscience, Computational
Publicado: (2023)

U12, a UDCA Derivative, Acts as an Anti-Hepatoma Drug Lead and Inhibits the mTOR/S6K1 and Cyclin/CDK Complex Pathways
por: Xu, Yang, et al.
Publicado: (2014)

Ursodeoxycholic acid exerts farnesoid X receptor-antagonistic effects on bile acid and lipid metabolism in morbid obesity
por: Mueller, Michaela, et al.
Publicado: (2015)

Pioglitazone Attenuates Atherosclerosis in Diabetic Mice by Inhibition of Receptor for Advanced Glycation End-Product (RAGE) Signaling
por: Gao, Hongli, et al.
Publicado: (2017)

Ursodeoxycholic Acid May Inhibit Environmental Aging-Associated Hyperpigmentation
por: Moon, Ik Jun, et al.
Publicado: (2021)

On the pathogenesis of atherosclerosis: enzymatic transformation of human low density lipoprotein to an atherogenic moiety
Publicado: (1995)

NCX 1000 Alone or in Combination with Vitamin E Reverses Experimental Nonalcoholic Steatohepatitis in the Rat Similarly to UDCA
por: Haddad, Yara, et al.
Publicado: (2011)

A network meta-analysis of the efficacy and side effects of udca-based therapies for primary sclerosing cholangitis
por: Zhu, Gui-Qi, et al.
Publicado: (2015)

Preclinical Evaluation of UDCA-Containing Oral Formulation in Mice for the Treatment of Wet Age-Related Macular Degeneration
por: Maharjan, Pooja, et al.
Publicado: (2019)

The relationship between disease activity and UDCA response criteria in primary biliary cholangitis: A cohort study
por: Jones, David E.J., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_l93bm4qlobkme0mkifrcfu7krs