The Toll-Like Receptor 4 (TLR4) Variant rs2149356 and Risk of Gout in European and Polynesian Sample Sets

Deposition of crystallized monosodium urate (MSU) in joints as a result of hyperuricemia is a central risk factor for gout. However other factors must exist that control the progression from hyperuricaemia to gout. A previous genetic association study has implicated the toll-like receptor 4 (TLR4) w...

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Detalles Bibliográficos
Autores principales: Rasheed, Humaira, McKinney, Cushla, Stamp, Lisa K., Dalbeth, Nicola, Topless, Ruth K., Day, Richard, Kannangara, Diluk, Williams, Kenneth, Smith, Malcolm, Janssen, Matthijs, Jansen, Tim L., Joosten, Leo A., Radstake, Timothy R., Riches, Philip L., Tausche, Anne-Kathrin, Lioté, Frederic, Lu, Leo, Stahl, Eli A., Choi, Hyon K., So, Alexander, Merriman, Tony R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726773/
https://www.ncbi.nlm.nih.gov/pubmed/26808548
http://dx.doi.org/10.1371/journal.pone.0147939

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