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Amidated and Ibuprofen-Conjugated Kyotorphins Promote Neuronal Rescue and Memory Recovery in Cerebral Hypoperfusion Dementia Model
Chronic brain ischemia is a prominent risk factor for neurological dysfunction and progression for dementias, including Alzheimer’s disease (AD). In rats, permanent bilateral common carotid artery occlusion (2VO) causes a progressive neurodegeneration in the hippocampus, learning deficits and memory...
Autores principales: | Sá Santos, Sónia, Santos, Sara M., Pinto, Antónia R. T., Ramu, Vasanthakumar G., Heras, Montserrat, Bardaji, Eduard, Tavares, Isaura, Castanho, Miguel A. R. B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726799/ https://www.ncbi.nlm.nih.gov/pubmed/26858637 http://dx.doi.org/10.3389/fnagi.2016.00001 |
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