Cargando…

Optical Imaging of PARP1 in Response to Radiation in Oral Squamous Cell Carcinoma

Targeting and inhibiting DNA repair pathways is a powerful strategy of controlling malignant growth. One such strategy includes the inhibition of PARP1, a central element in the intracellular DNA damage response. To determine and visualize the expression and intercellular distribution of PARP1 in vi...

Descripción completa

Detalles Bibliográficos
Autores principales: Kossatz, Susanne, Weber, Wolfgang A., Reiner, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726809/
https://www.ncbi.nlm.nih.gov/pubmed/26808835
http://dx.doi.org/10.1371/journal.pone.0147752