Type I and Type II Interferon Coordinately Regulate Suppressive Dendritic Cell Fate and Function during Viral Persistence

Persistent viral infections are simultaneously associated with chronic inflammation and highly potent immunosuppressive programs mediated by IL-10 and PDL1 that attenuate antiviral T cell responses. Inhibiting these suppressive signals enhances T cell function to control persistent infection; yet, t...

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Detalles Bibliográficos
Autores principales: Cunningham, Cameron R., Champhekar, Ameya, Tullius, Michael V., Dillon, Barbara Jane, Zhen, Anjie, de la Fuente, Justin Rafael, Herskovitz, Jonathan, Elsaesser, Heidi, Snell, Laura M., Wilson, Elizabeth B., de la Torre, Juan Carlos, Kitchen, Scott G., Horwitz, Marcus A., Bensinger, Steven J., Smale, Stephen T., Brooks, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726812/
https://www.ncbi.nlm.nih.gov/pubmed/26808628
http://dx.doi.org/10.1371/journal.ppat.1005356

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