Engineering Infectious cDNAs of Coronavirus as Bacterial Artificial Chromosomes

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The large size of the coronavirus (CoV) genome (around 30 kb) and the instability in bacteria of plasmids carrying CoV replicase sequences represent serious restrictions for the development of CoV infectious clones using reverse genetic systems similar to those used for smaller positive sense RNA vi...

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Detalles Bibliográficos
Autores principales: Almazán, Fernando, Márquez-Jurado, Silvia, Nogales, Aitor, Enjuanes, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726977/
https://www.ncbi.nlm.nih.gov/pubmed/25720478
http://dx.doi.org/10.1007/978-1-4939-2438-7_13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726977/
https://www.ncbi.nlm.nih.gov/pubmed/25720478
http://dx.doi.org/10.1007/978-1-4939-2438-7_13

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