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Melittin suppresses cathepsin S-induced invasion and angiogenesis via blocking of the VEGF-A/VEGFR-2/MEK1/ERK1/2 pathway in human hepatocellular carcinoma

Melittin, a significant constituent of Apis mellifera (honeybee) venom, is a water-soluble toxic peptide that has traditionally been used as an antitumor agent. However, the underlying mechanisms by which it inhibits tumor cell growth and angiogenesis remain to be elucidated. In the present study, s...

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Detalles Bibliográficos
Autores principales:	ZHANG, ZHI, ZHANG, HANGUANG, PENG, TAO, LI, DONGDONG, XU, JING
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727048/ https://www.ncbi.nlm.nih.gov/pubmed/26870255 http://dx.doi.org/10.3892/ol.2015.3957

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