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Epigenetic silencing of CREB3L1 by DNA methylation is associated with high-grade metastatic breast cancers with poor prognosis and is prevalent in triple negative breast cancers

BACKGROUND: CREB3L1 (cAMP-responsive element-binding protein 3-like protein 1), a member of the unfolded protein response, has recently been identified as a metastasis suppressor in both breast and bladder cancer. METHODS: Quantitative real time PCR (qPCR) and immunoblotting were used to determine t...

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Detalles Bibliográficos
Autores principales:	Ward, Alison K., Mellor, Paul, Smith, Shari E., Kendall, Stephanie, Just, Natasha A., Vizeacoumar, Frederick S., Sarker, Sabuj, Phillips, Zoe, Alvi, Riaz, Saxena, Anurag, Vizeacoumar, Franco J., Carlsen, Svein A., Anderson, Deborah H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727399/ https://www.ncbi.nlm.nih.gov/pubmed/26810754 http://dx.doi.org/10.1186/s13058-016-0672-x

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