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T-bet expression in CD8+ T cells associated with chronic hepatitis B virus infection

BACKGROUND: The mechanisms leading to virus-specific CD8+ T cell dysfuction in chronic hepatitis B virus (HBV) infection remain to be elucidated. Our study focused on the role of transcription factor T-bet in HBV infection because it is a crucial regulator of T cell immunity. METHODS: We assessed th...

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Detalles Bibliográficos
Autores principales:	Fan, Rongshan, Lan, Yinghua, Chen, Jiwang, Huang, Yanxin, Yan, Qin, Jiang, Lisheng, Song, Shupeng, Li, Yongguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727400/ https://www.ncbi.nlm.nih.gov/pubmed/26809262 http://dx.doi.org/10.1186/s12985-016-0473-y

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