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Coronavirus reverse genetic systems: Infectious clones and replicons

Coronaviruses (CoVs) infect humans and many animal species, and are associated with respiratory, enteric, hepatic, and central nervous system diseases. The large size of the CoV genome and the instability of some CoV replicase gene sequences during its propagation in bacteria, represent serious obst...

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Detalles Bibliográficos
Autores principales: Almazán, Fernando, Sola, Isabel, Zuñiga, Sonia, Marquez-Jurado, Silvia, Morales, Lucia, Becares, Martina, Enjuanes, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727449/
https://www.ncbi.nlm.nih.gov/pubmed/24930446
http://dx.doi.org/10.1016/j.virusres.2014.05.026