Screening of Panamanian Plants for Cosmetic Properties, and HPLC-Based Identification of Constituents with Antioxidant and UV-B Protecting Activities

A library of 600 taxonomically diverse Panamanian plant extracts was screened for DPPH scavenging and UV-B protective activities, and the methanolic extracts of Mosquitoxylum jamaicense, Combretum cacoucia, and Casearia commersionia were submitted to HPLC-based activity profiling. The compounds loca...

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Autores principales: Guldbrandsen, Niels, De Mieri, Maria, Gupta, Mahabir, Liakou, Eleni, Pratsinis, Harris, Kletsas, Dimitris, Chaita, Eliza, Aligiannis, Nektarios, Skaltsounis, Alexios-Leandros, Hamburger, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Austrian Journal of Pharmaceutical Sciences 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727770/
https://www.ncbi.nlm.nih.gov/pubmed/26839809
http://dx.doi.org/10.3797/scipharm.1409-12
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author Guldbrandsen, Niels
De Mieri, Maria
Gupta, Mahabir
Liakou, Eleni
Pratsinis, Harris
Kletsas, Dimitris
Chaita, Eliza
Aligiannis, Nektarios
Skaltsounis, Alexios-Leandros
Hamburger, Matthias
author_facet Guldbrandsen, Niels
De Mieri, Maria
Gupta, Mahabir
Liakou, Eleni
Pratsinis, Harris
Kletsas, Dimitris
Chaita, Eliza
Aligiannis, Nektarios
Skaltsounis, Alexios-Leandros
Hamburger, Matthias
author_sort Guldbrandsen, Niels
collection PubMed
description A library of 600 taxonomically diverse Panamanian plant extracts was screened for DPPH scavenging and UV-B protective activities, and the methanolic extracts of Mosquitoxylum jamaicense, Combretum cacoucia, and Casearia commersionia were submitted to HPLC-based activity profiling. The compounds located in the active time windows were isolated and identified as gallic acid derivatives and flavonoids. Gallic acid methyl ester (3) and digallic acid derivatives (2, 6) showed the highest DPPH scavenging activity (<10 μg/mL), while protocatechuic acid (7) and isoquercitrin (10) exhibited the highest UV-B protective properties.
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spelling pubmed-47277702016-02-02 Screening of Panamanian Plants for Cosmetic Properties, and HPLC-Based Identification of Constituents with Antioxidant and UV-B Protecting Activities Guldbrandsen, Niels De Mieri, Maria Gupta, Mahabir Liakou, Eleni Pratsinis, Harris Kletsas, Dimitris Chaita, Eliza Aligiannis, Nektarios Skaltsounis, Alexios-Leandros Hamburger, Matthias Sci Pharm Research Article A library of 600 taxonomically diverse Panamanian plant extracts was screened for DPPH scavenging and UV-B protective activities, and the methanolic extracts of Mosquitoxylum jamaicense, Combretum cacoucia, and Casearia commersionia were submitted to HPLC-based activity profiling. The compounds located in the active time windows were isolated and identified as gallic acid derivatives and flavonoids. Gallic acid methyl ester (3) and digallic acid derivatives (2, 6) showed the highest DPPH scavenging activity (<10 μg/mL), while protocatechuic acid (7) and isoquercitrin (10) exhibited the highest UV-B protective properties. The Austrian Journal of Pharmaceutical Sciences 2015 2014-10-15 /pmc/articles/PMC4727770/ /pubmed/26839809 http://dx.doi.org/10.3797/scipharm.1409-12 Text en Copyright: © Guldbrandsen et al. http://creativecommons.org/licenses/by/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Guldbrandsen, Niels
De Mieri, Maria
Gupta, Mahabir
Liakou, Eleni
Pratsinis, Harris
Kletsas, Dimitris
Chaita, Eliza
Aligiannis, Nektarios
Skaltsounis, Alexios-Leandros
Hamburger, Matthias
Screening of Panamanian Plants for Cosmetic Properties, and HPLC-Based Identification of Constituents with Antioxidant and UV-B Protecting Activities
title Screening of Panamanian Plants for Cosmetic Properties, and HPLC-Based Identification of Constituents with Antioxidant and UV-B Protecting Activities
title_full Screening of Panamanian Plants for Cosmetic Properties, and HPLC-Based Identification of Constituents with Antioxidant and UV-B Protecting Activities
title_fullStr Screening of Panamanian Plants for Cosmetic Properties, and HPLC-Based Identification of Constituents with Antioxidant and UV-B Protecting Activities
title_full_unstemmed Screening of Panamanian Plants for Cosmetic Properties, and HPLC-Based Identification of Constituents with Antioxidant and UV-B Protecting Activities
title_short Screening of Panamanian Plants for Cosmetic Properties, and HPLC-Based Identification of Constituents with Antioxidant and UV-B Protecting Activities
title_sort screening of panamanian plants for cosmetic properties, and hplc-based identification of constituents with antioxidant and uv-b protecting activities
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727770/
https://www.ncbi.nlm.nih.gov/pubmed/26839809
http://dx.doi.org/10.3797/scipharm.1409-12
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