Cargando…

Forced Degradation Behaviour of Fluphenazine Hydrochloride by LC and Characterization of its Oxidative Degradation Product by LC–MS/MS

A novel, stability-indicating high-performance liquid chromatographic (HPLC) method is delivered for the determination of fluphenazine hydrochloride (FPZ) and its degradation products. The forced degradation testing of FPZ was carried out for hydrolytic, oxidative, photolytic, and thermal degradatio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Thummar, Kashyap N., Ghava, Dilip J., Mistry, Anvi, Vachhani, Ashish, Sheth, Navin R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Austrian Journal of Pharmaceutical Sciences 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727772/ https://www.ncbi.nlm.nih.gov/pubmed/26839816 http://dx.doi.org/10.3797/scipharm.1411-04

Ejemplares similares

Identification of Forced Degradation Products of Itopride by LC-PDA and LC-MS
por: Joshi, Payal, et al.
Publicado: (2011)

Characterization of forced degradation products of toloxatone by LC-ESI-MS/MS
por: Skibiński, Robert, et al.
Publicado: (2018)

LC, MS(n) and LC–MS/MS studies for the characterization of degradation products of amlodipine
por: Tiwari, Ravi N., et al.
Publicado: (2015)

LC and LC–MS/MS studies for the identification and characterization of degradation products of acebutolol
por: Rakibe, Uday, et al.
Publicado: (2018)

Characterization of the Oxidative Degradation Product of Darunavir by LC-MS/MS
por: Yamjala, Karthik, et al.
Publicado: (2015)

Study of forced degradation behavior of pramlintide acetate by HPLC and LC–MS
por: Yuan, Yu, et al.
Publicado: (2017)

LC–UV and LC–MS evaluation of stress degradation behavior of desvenlafaxine
por: Pawar, Shubhangi M., et al.
Publicado: (2012)

Multivariate Chemometric Comparison of Forced Degradation and Electrochemical Oxidation LC–MS Profiles of Maraviroc
por: Wroński, Michał, et al.
Publicado: (2023)

The LC-QTOF-MS/MS analysis of acid degradation products of Rifaximin, an antibiotic
por: Yaseen, Saima Baig, et al.
Publicado: (2022)

Identification and Characterization of Hydrolytic Degradation Products of Cefditoren Pivoxil using LC and LC-MS/TOF
por: Gawande, V. T., et al.
Publicado: (2015)

Selective separation, detection of zotepine and mass spectral characterization of degradants by LC–MS/MS/QTOF
por: Talluri, M.V.N. Kumar, et al.
Publicado: (2014)

Identification of degradation impurity of TGR5 receptor agonist-ZY12201 by LC–MS technique during force degradation study
por: Sojitra, Chandrakant, et al.
Publicado: (2021)

Fecal metabolite analysis of Japanese macaques in Yakushima by LC-MS/MS and LC-QTOF-MS
por: TSUCHIDA, Sayaka, et al.
Publicado: (2021)

Evaluation of LC-MS and LC×LC-MS in analysis of zebrafish embryo samples for comprehensive lipid profiling
por: Xu, Mengmeng, et al.
Publicado: (2020)

Quantification of Degradation Products Formed during Heat Sterilization of Glucose Solutions by LC-MS/MS: Impact of Autoclaving Temperature and Duration on Degradation
por: Leitzen, Sarah, et al.
Publicado: (2021)

Kinetics and Characterization of Degradation Products of Dihydralazine and Hydrochlorothiazide in Binary Mixture by HPLC-UV, LC-DAD and LC–MS Methods
por: Gumieniczek, Anna, et al.
Publicado: (2018)

Degradation Dynamics and Residue Analysis of Four Propiconazole Stereoisomers in “Fengtang” Plum during Storage by LC-MS/MS
por: Deng, Pengyu, et al.
Publicado: (2023)

Largazole Pharmacokinetics in Rats by LC-MS/MS
por: Yu, Mingming, et al.
Publicado: (2014)

Application of LC–MS/MS in the Mycotoxins Studies
por: Gámiz-Gracia, Laura, et al.
Publicado: (2020)

Pigments’ analysis of Citrus juicing making by‐products by LC‐MS/MS and LC‐DAD
por: Myrtsi, Eleni D., et al.
Publicado: (2022)

Development of a Forced Degradation Profile of Alosetron by Single Mode Reversed-Phase HPLC, LC-MS, and its Validation
por: Karthik, Yamjala, et al.
Publicado: (2015)

Development of Validated and Stability-Indicating LC-DAD and LC-MS/MS Methods for Determination of Avanafil in Pharmaceutical Preparations and Identification of a Novel Degradation Product by LCMS-IT-TOF
por: CAN, Nafiz Öncü
Publicado: (2018)

Simultaneous detection of lysine metabolites by a single LC–MS/MS method: monitoring lysine degradation in mouse plasma
por: Pena, Izabella A., et al.
Publicado: (2016)

LC-MS Method for Studying the Pharmacokinetics and Bioequivalence of Clonidine Hydrochloride in Healthy Male Volunteers
por: Danafar, Hossein, et al.
Publicado: (2016)

LC-MS/MS and LC-UV Determination of Moniliformin by Adding Lanthanide Ions to the Mobile Phase
por: Bertuzzi, Terenzio, et al.
Publicado: (2019)

Fast and high-throughput LC-MS characterization, and peptide mapping of engineered AAV capsids using LC-MS/MS
por: Lam, Anh K., et al.
Publicado: (2022)

Integrated LC-MS/MS system for plant metabolomics
por: Sawada, Yuji, et al.
Publicado: (2013)

Comparison of Flow Injection-MS/MS and LC-MS/MS for the Determination of Ochratoxin A
por: Zhang, Kai
Publicado: (2021)

Development, Validation, and Comparison of Two Mass Spectrometry Methods (LC-MS/HRMS and LC-MS/MS) for the Quantification of Rituximab in Human Plasma
por: Millet, Aurélien, et al.
Publicado: (2021)

Co-Occurrence of Hypoglycin A and Hypoglycin B in Sycamore and Box Elder Maple Proved by LC-MS/MS and LC-HR-MS
por: El-Khatib, Ahmed H., et al.
Publicado: (2022)

The influence of effective microorganisms (EM) and yeast on the degradation of strobilurins and carboxamides in leafy vegetables monitored by LC-MS/MS and health risk assessment
por: Wołejko, Elżbieta, et al.
Publicado: (2015)

A stability-indicating LC–MS/MS method for zidovudine: Identification, characterization and toxicity prediction of two major acid degradation products
por: Devrukhakar, Prashant S., et al.
Publicado: (2017)

Stoichiometric Quantification of Akt Phosphorylation Using LC-MS/MS
por: Atrih, Abdelmadjid, et al.
Publicado: (2009)

Quantitation of cyclic dinucleotides by reversed-phase LC-MS/MS
por: Spangler, Christian, et al.
Publicado: (2009)

Optimal precursor ion selection for LC-MALDI MS/MS
por: Zerck, Alexandra, et al.
Publicado: (2013)

Visualization of LC‐MS/MS proteomics data in MaxQuant
por: Tyanova, Stefka, et al.
Publicado: (2015)

Determination of Salicylic Acid in Feed Using LC-MS/MS
por: Protasiuk, Edyta, et al.
Publicado: (2018)

Targeted Determination of Tissue Energy Status by LC-MS/MS
por: Fu, Xiaorong, et al.
Publicado: (2019)

Lipid Discovery by Combinatorial Screening and Untargeted LC-MS/MS
por: Bilgin, Mesut, et al.
Publicado: (2016)

Development and validation of Lenalidomide in human plasma by LC-MS/MS
por: Ranganathan, Premanand, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_qq5ktk4vu1smsqipdg134ssjvf