Synthesis and Anti-Platelet Activity of Thiosulfonate Derivatives Containing a Quinone Moiety

Thiosulfonate derivatives based on quinones were synthesized for studying “structure-activity relationship” compounds with an acylated and a free amino-group. Anti-platelet activity of the synthesized compounds was determined and the influence of substituents on the activity of the derivatives was a...

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Detalles Bibliográficos
Autores principales: Bolibrukh, Khrystyna, Polovkovych, Svyatoslav, Khoumeri, Omar, Halenova, Tetyana, Nikolaeva, Irina, Savchuk, Olexiy, Terme, Thierry, Vanelle, Patrice, Lubenets, Vira, Novikov, Volodymyr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Austrian Journal of Pharmaceutical Sciences 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727794/
https://www.ncbi.nlm.nih.gov/pubmed/26839819
http://dx.doi.org/10.3797/scipharm.1411-14
Descripción
Sumario:Thiosulfonate derivatives based on quinones were synthesized for studying “structure-activity relationship” compounds with an acylated and a free amino-group. Anti-platelet activity of the synthesized compounds was determined and the influence of substituents on the activity of the derivatives was assessed.

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