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Development of a Forced Degradation Profile of Alosetron by Single Mode Reversed-Phase HPLC, LC-MS, and its Validation
Determination of alosetron in the presence of its degradation products was studied and validated by a novel HPLC method. The separation of the drug and its degradation products was achieved with the Jones Chromatography C(18) analytical column (150 mm x 4.6 mm; 3 µm) with a stationary phase in isocr...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Austrian Journal of Pharmaceutical Sciences
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727810/ https://www.ncbi.nlm.nih.gov/pubmed/26839817 http://dx.doi.org/10.3797/scipharm.1411-07 |