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Rational design of alpha-helical tandem repeat proteins with closed architectures
Tandem repeat proteins, which are formed by repetition of modular units of protein sequence and structure, play important biological roles as macromolecular binding and scaffolding domains, enzymes, and building blocks for the assembly of fibrous materials(1,2). The modular nature of repeat proteins...
Autores principales: | Doyle, Lindsey, Hallinan, Jazmine, Bolduc, Jill, Parmeggiani, Fabio, Baker, David, Stoddard, Barry L., Bradley, Philip |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727831/ https://www.ncbi.nlm.nih.gov/pubmed/26675735 http://dx.doi.org/10.1038/nature16191 |
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