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Rational design of alpha-helical tandem repeat proteins with closed architectures

Tandem repeat proteins, which are formed by repetition of modular units of protein sequence and structure, play important biological roles as macromolecular binding and scaffolding domains, enzymes, and building blocks for the assembly of fibrous materials(1,2). The modular nature of repeat proteins...

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Detalles Bibliográficos
Autores principales: Doyle, Lindsey, Hallinan, Jazmine, Bolduc, Jill, Parmeggiani, Fabio, Baker, David, Stoddard, Barry L., Bradley, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727831/
https://www.ncbi.nlm.nih.gov/pubmed/26675735
http://dx.doi.org/10.1038/nature16191

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