Molecular Basis of Orb2 Amyloidogenesis and Blockade of Memory Consolidation

Amyloids are ordered protein aggregates that are typically associated with neurodegenerative diseases and cognitive impairment. By contrast, the amyloid-like state of the neuronal RNA binding protein Orb2 in Drosophila was recently implicated in memory consolidation, but it remains unclear what feat...

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Detalles Bibliográficos
Autores principales: Hervás, Rubén, Li, Liying, Majumdar, Amitabha, Fernández-Ramírez, María del Carmen, Unruh, Jay R., Slaughter, Brian D., Galera-Prat, Albert, Santana, Elena, Suzuki, Mari, Nagai, Yoshitaka, Bruix, Marta, Casas-Tintó, Sergio, Menéndez, Margarita, Laurents, Douglas V., Si, Kausik, Carrión-Vázquez, Mariano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727891/
https://www.ncbi.nlm.nih.gov/pubmed/26812143
http://dx.doi.org/10.1371/journal.pbio.1002361

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