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Cardiac Effects of Attenuating Gsα - Dependent Signaling

AIMS: Inhibition of β-adrenergic signalling plays a key role in treatment of heart failure. Gsα is essential for β-adrenergic signal transduction. In order to reduce side-effects of beta-adrenergic inhibition diminishing β-adrenergic signalling in the heart at the level of Gsα is a promising option....

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Detalles Bibliográficos
Autores principales: Streit, Marcus R., Weiss, Celine S., Meyer, Sören, Ochs, Marco M., Hagenmueller, Marco, Riffel, Johannes H., Buss, Sebastian J., Heger, Thomas, Katus, Hugo A., Hardt, Stefan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727906/
https://www.ncbi.nlm.nih.gov/pubmed/26811901
http://dx.doi.org/10.1371/journal.pone.0146988