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Ongoing Remission Nineteen Years after High-dose Chemotherapy for Oligometastatic Breast Cancer; What Can We Learn from this Patient?

Metastatic breast cancer is generally considered incurable. However, some patients show an exceptional response to treatment and enjoy long-term survival in good health. Here, we present a remarkable example of a patient who is still in remission 19 years after high-dose chemotherapy and locoregiona...

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Autores principales: Steenbruggen, Tessa G, Linn, Sabine C, Rodenhuis, Sjoerd, Sonke, Gabe S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727954/
https://www.ncbi.nlm.nih.gov/pubmed/26848422
http://dx.doi.org/10.7759/cureus.433
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author Steenbruggen, Tessa G
Linn, Sabine C
Rodenhuis, Sjoerd
Sonke, Gabe S
author_facet Steenbruggen, Tessa G
Linn, Sabine C
Rodenhuis, Sjoerd
Sonke, Gabe S
author_sort Steenbruggen, Tessa G
collection PubMed
description Metastatic breast cancer is generally considered incurable. However, some patients show an exceptional response to treatment and enjoy long-term survival in good health. Here, we present a remarkable example of a patient who is still in remission 19 years after high-dose chemotherapy and locoregional treatment for limited oligometastatic breast cancer. We will outline our rationale for this treatment to explain her excellent response and suggest strategies to select larger patient groups that could similarly benefit from existing treatment approaches.
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spelling pubmed-47279542016-02-04 Ongoing Remission Nineteen Years after High-dose Chemotherapy for Oligometastatic Breast Cancer; What Can We Learn from this Patient? Steenbruggen, Tessa G Linn, Sabine C Rodenhuis, Sjoerd Sonke, Gabe S Cureus Oncology Metastatic breast cancer is generally considered incurable. However, some patients show an exceptional response to treatment and enjoy long-term survival in good health. Here, we present a remarkable example of a patient who is still in remission 19 years after high-dose chemotherapy and locoregional treatment for limited oligometastatic breast cancer. We will outline our rationale for this treatment to explain her excellent response and suggest strategies to select larger patient groups that could similarly benefit from existing treatment approaches. Cureus 2015-12-24 /pmc/articles/PMC4727954/ /pubmed/26848422 http://dx.doi.org/10.7759/cureus.433 Text en Copyright © 2015, Steenbruggen et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Oncology
Steenbruggen, Tessa G
Linn, Sabine C
Rodenhuis, Sjoerd
Sonke, Gabe S
Ongoing Remission Nineteen Years after High-dose Chemotherapy for Oligometastatic Breast Cancer; What Can We Learn from this Patient?
title Ongoing Remission Nineteen Years after High-dose Chemotherapy for Oligometastatic Breast Cancer; What Can We Learn from this Patient?
title_full Ongoing Remission Nineteen Years after High-dose Chemotherapy for Oligometastatic Breast Cancer; What Can We Learn from this Patient?
title_fullStr Ongoing Remission Nineteen Years after High-dose Chemotherapy for Oligometastatic Breast Cancer; What Can We Learn from this Patient?
title_full_unstemmed Ongoing Remission Nineteen Years after High-dose Chemotherapy for Oligometastatic Breast Cancer; What Can We Learn from this Patient?
title_short Ongoing Remission Nineteen Years after High-dose Chemotherapy for Oligometastatic Breast Cancer; What Can We Learn from this Patient?
title_sort ongoing remission nineteen years after high-dose chemotherapy for oligometastatic breast cancer; what can we learn from this patient?
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727954/
https://www.ncbi.nlm.nih.gov/pubmed/26848422
http://dx.doi.org/10.7759/cureus.433
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