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Discrete spatial organization of TGFβ receptors couples receptor multimerization and signaling to cellular tension

Cell surface receptors are central to the cell's ability to generate coordinated responses to the multitude of biochemical and physical cues in the microenvironment. However, the mechanisms by which receptors enable this concerted cellular response remain unclear. To investigate the effect of c...

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Detalles Bibliográficos
Autores principales: Rys, Joanna P, DuFort, Christopher C, Monteiro, David A, Baird, Michelle A, Oses-Prieto, Juan A, Chand, Shreya, Burlingame, Alma L, Davidson, Michael W, Alliston, Tamara N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728123/
https://www.ncbi.nlm.nih.gov/pubmed/26652004
http://dx.doi.org/10.7554/eLife.09300